Research Group MBGU Publications

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Anuranjan AnandHemalatha BalaramManeesha InamdarUdaykumar RangaKundu Tapas K.
M. R. S. RaoKaustuv SanyalNamita SuroliaJames P. Clement ChelliahRavi Manjithaya


  1. Pallavi Kakade, Kasturi Mahadik, Kaustuv Sanyal, K N Balaji and Valakunja Nagaraja, Two negative regulators of biofilm development exhibit functional divergence in conferring virulence potential to Candida albicans, FEMS Yeast Research (2018). In Press.

  2. Vikas Yadav, Lakshmi Sreekumar, Krishnendu Guin and Kaustuv Sanyal^, Five pillars of centromeric chromatin in fungal pathogens, PLoS Pathogens (2018). In Press.

  3. Vikas Yadav^ and Kaustuv Sanyal^, Sad1 spatio-temporally regulates kinetochore clustering to ensure high fidelity chromosome segregation in the human fungal pathogen Cryptococcus neoformans, mSphere (2018). In Press.

  4. Jiaul Hoque, Vikas Yadav, R G Prakash, Kaustuv Sanyal and Jayanta Haldar, Dual function polymer-silver nanocomposites for rapid killing of microbes and inhibiting biofilms, ACS Biomaterials Science and Bioengineering (2018). In Press.

  5. Vikas Yadav, Sheng Sun, R Blake Billmyre, Bhagya C Thimmappa, Terrance Shea, Robert Linter, Guus Bakkeren, Christina A. Cuomo, Joseph Heitman and Kaustuv Sanyal^, RNAi is a critical determinant of centromere evolution in closely related fungi, Proceedings of the National Academy of Sciences of the United States of America 115, 3108 - 3113 (2018).

  6. Kim J-H et al, Report of the International Stem Cell Banking Initiative Workshop Activity: Current Hurdles and Progress in Seed-Stock Banking of Human Pluripotent Stem Cells, Stem Cells Translational Medicine 6, 1956 - 1962 (2018).

  7. Laxmi Shanker Rai, Rima Singha, Priya Brahma and Kaustuv Sanyal^, Epigenetic determinants of phenotypic plasticity in Candida albicans  , Fungal Biology Reviews 32, 10 - 19 (2018).

  8. Simi Muraleedharana, Aksah Sama, Helen Skaerb and Maneesha S. Inamdara, Networks that link cytoskeletal regulators and diaphragm proteins underpin filtration function in Drosophila nephrocytes, Experimental Cell Research (2017). In Press.

  9. Sheng Sun, Vikas Yadav, ........, Kaustuv Sanyal and Joseph Heitman, Fungal genome and mating system transitions facilitated by chromosomal translocations involving intercentromeric recombination, PLOS Biology (2017).

  10. Sophie Altamirano, Diana Fang, Charles Simmons, Shreyas Sridhar, Peipei Wu, Kaustuv Sanyal and Lukasz Kozubowski, Fluconazole-induced ploidy change in Cryptococcus neoformans results from the uncoupling of cell growth and nuclear division, mSphere (2017).

  11. Chandradhish Ghosh, Vikas Yadav, ......., Kaustuv Sanyal and Jayanta Haldar, Aryl-alkyl-lysines: Membrane-active fungicides that act against biofilms of Candida albicans, ACS Infectious Diseases 3, 293 - 301 (2017).

  12. Kadilkar R.J.† , Ray A.†, Chetan D.R., Sinha AR., Magadi S.S., Kulkarni V. and Inamdar M.S.*, Differential modulation of the cellular and humoral immune responses in Drosophila is mediated by the endosomal ARF1-Asrij axis, Scientific Reports 7, (2017).

  13. Yafeng Zhu, ..., Sundar Ram Sankaranarayanan, Rahul Siddharthan, Kaustuv Sanyal, .... and Janne Lehtio, Proteogenomics produces comprehensive and highly accurate protein-coding gene annotation in a complete genome assembly of Malassezia sympodialis, Nucleic Acids Research 45, 2629 - 2643 (2017).

  14. Jiaul Hoque, Utsarga Adhikary, Vikas Yadav, ..., Kaustuv Sanyal and Jayanta Haldar, Chitosan Derivatives Active against Multidrug-Resistant Bacteria and Pathogenic Fungi: In Vivo Evaluation as Topical Antimicrobials, Molecular Pharmaceutics 13, 3578 - 3589 (2016).

  15. Aritreyee Datta*, Vikas Yadav*, ............, Kaustuv Sanyal, Ayyalusamy Ramamoorthy and Anirban Bhunia, Mode of Action of a Designed Antimicrobial Peptide: High Efficiency in Killing of the Human Fungal Pathogen Cryptococcus neoformans, Biophysical Journal 111, 1724 - 1737 (2016).

  16. Pallavi Kakade, Parag Sadhale, Kaustuv Sanyal and Valakunja Nagaraja, ZCF32, a fungus specific Zn(II)2-Cys6 transcription factor, is a repressor of the biofilm development in the human pathogen Candida albicans, Scientific Reports (2016).

  17. Sudhir H. Ranganath, Zhixiang Tong, Oren Levy, Keir Martyn, Jeffrey M. Karp and Maneesha S. Inamdar, Controlled Inhibition of the Mesenchymal Stromal Cell Pro-inflammatory Secretome via Microparticle Engineering, Stem Cell Reports (2016). In Press.

  18. Gautam Chatterjee, Sundar Ram Sankaranarayanan, Krishnendu Guin, Yogitha Thattikota, Sreedevi Padmanabhan, Rahul Siddharthan and Kaustuv Sanyal^, Repeat-associated fission yeast-like regional centromeres in the ascomycetous budding yeast Candida tropicalis  , PLoS Genetics (2016).

  19. Sreyoshi Mitra, Laxmi Shanker Rai, Gautam Chatterjee and Kaustuv Sanyal^,  Chromatin immunoprecipitation (ChIP) assay in Candida albicans, Methods in Molecular Biology 1356, 43 - 57 (2016).

  20. Sourav Roy, Lakshmeesha K. Nagappa, Vasudeva S. P. and Hemalatha Balaram, Kinetic mechanism of Plasmodium falciparum hypoxanthine-guanine-xanthine phosphoribosyltransferase, Molecular and Biochemical Parasitology 204, 111 - 120 (2015).

  21. Sourav Roy, Tarak Karmakar, Vasudeva S. P., Lakshmeesha K. Nagappa, Sundaram Balasubramanian and Hemalatha Balaram, Slow ligand-induced conformational switch increases the catalytic rate in Plasmodium falciparum hypoxanthine guanine xanthine phosphoribosyltransferase, Molecular Biosystems 11, 1410 - 1424 (2015).

  22. Bharath Srinivasan, Lakshmeesha Kempaiah Nagappa, Arpit Shukla and Hemalatha Balaram, Prediction of substrate specificity and preliminary kinetic characterization of the hypothetical protein PVX_123945 fromPlasmodium vivax, Experimental Parasitology 151, 56 - 63 (2015).

  23. Lionel Ballut, Sebastien Violot, Santosh Shivakumaraswamy, Lakshmi Prasoona Thota, Manu Sathya, Jyothirmai Kunala, Bauke W. Dijkstra, Raphael Terreux, Richard Haser, Hemalatha Balaram and Nushin Aghajari, Active site coupling in Plasmodium falciparum GMP synthetase is triggered by domain rotation, Nature Communications 6, (2015).

  24. Deeti K. Shetty and Maneesha S. Inamdar, Generation of transgenic human embryonic stem cell line BJNhem20-OCIAD1-OV, Lab Resource: Stem Cell Research (2015). In Press.

  25. Ronak Shetty, Deeti K. Shetty and Maneesha S. Inamdar, Generation of human embryonic stem cell line expressing green fluorescent protein, Lab Resource: Stem Cell Research (2015). In Press.

  26. T. S. Suryanarayanan, Vengat Gopal, Dinkar Sahal and Kaustuv Sanyal, Establishing a national fungal genetic resource to enhance the bioeconomy, Current Science 109, 1033 - 1037 (2015).

  27. Sabyasachi Sutradhar*, Vikas Yadav*, Shreyas Sridhar*, Lakshmi Sreekumar, Dibyendu Bhattacharyya, Santanu Kumar Ghosh, Raja Paul^ and Kaustuv Sanyal^, A comprehensive model to predict mitotic division in budding yeasts  , Molecular Biology of the Cell 26, 3954 - 3965 (2015).

  28. Nishant K.T.^ and Kaustuv Sanyal^, The good, the bad and the ugly: How to protect genome stability from potential threats , Bioessays 37, 717 - 720 (2015).

  29. Andrews P et al., Points to consider in the development of seed stocks of pluripotent stem cells for clinical applications: International Stem Cell Banking Initiative (ISCBI). Regenerative Medicine Vol. 10, No. 2s, Pages 1-44 , DOI 10.2217/rme.14.93, Regenerative medicine 10, 1 - 44 (2015).

  30. Neha Varshney*, Alida Schaekel*, Rima Singha, Tanmoy Chakraborty, Lasse van Wijlick, Joachim F. Ernst^ and Kaustuv Sanyal^, A surprising role for the Sch9 protein kinase in chromosome segregation in Candida albicans, Genetics 199, 671 - 674 (2015).

  31. Jiaul Hoque, Padma Akkapeddi, Vikas Yadav, Goutham B Manjunath, Divakara S. S. M. Uppu, Mohini Mohan Konai, Venkateswarlu Yarlagadda, Kaustuv Sanyal and Jayanta Haldar, Broad spectrum antibacterial and antifungal polymeric paint materials: synthesis, structure-activity relationship and membrane-active mode of action, ACS Appl. Mater. Interfaces 7, 1804 - 1815 (2015).

  32. Akhade VS, Arun G, Donakonda S and Satyanarayana Rao MR, Genome wide chromatin occupancy of mrhl RNA and its role in gene regulation in mouse spermatogonial cells, RNA Biology 11, (2014).

  33. Pentakota SK, Sandhya S, P Sikarwar A, Chandra N and Satyanarayana Rao MR, Mapping post-translational modifications of mammalian testicular specific histone variant TH2B in tetraploid and haploid germ cells and their implications on the dynamics of nucleosome structure, J. Proteome Research 13, (2014).

  34. Bharath Srinivasan, Farhad Forouhar, Arpit Shukla, Sonia Kulkarni, Chethana Sampangi and Hemalatha Balaram, Allosteric regulation and substrate activation in cytosolic nucleotidase-II from Legionella pneumophila, FEBS J (2014).

  35. Sreyoshi Mitra, Jonathan Gomez-Raja, German Larriba, Dharani Dhar Dubey and Kaustuv Sanyal^, Rad51-Rad52 mediated maintenance of centromeric chromatin in Candida albicans , PLoS Genetics 10, (2014).

  36. Guilhem Janbon, Kate L. Ormerod, Damien Paulet, Edmond J. Byrnes III, Vikas Yadav, Gautam Chatterjee, (+41 authors), Kaustuv Sanyal, Joseph Heitman, James A. Fraser, Christina A. Cuomo and Fred S. Dietrich, Analysis of the genome and transcriptome of Cryptococcus neoformans var. grubii reveals complex RNA expression and microevolution leading to virulence attenuation, PLoS Genetics (2014).

  37. Arivazhagan Arimappamagan, Kumaravel Somasundaram , ...... and Manchanahalli R. Sathyanarayana Rao, A Fourteen Gene GBM Prognostic Signature Identifies Association of Immune Response Pathway and Mesenchymal Subtype with High Risk Group, Plos One 8, (2013).

  38. Verma, G., & Surolia, N. (2013). < i> Plasmodium falciparum CENH3 is able to functionally complement Cse4p and its, C-terminus is essential for centromere function. Molecular and biochemical parasitology, molecular and biochemical parasitology (2013).

  39. James P Clement, Emin D Ozkan, Massimilano Aceti, Courtney A Miller and Gavin Rumbaugh, SYNGAP1 links the maturation rate of excitatory synapses to the duration of critical period synaptic plasticity, Journal of Neuroscience 25, 10447 - 52 (2013).

  40. Ramana LN, Sharma S, Sethuraman S, Ranga U, Krishnan UM, Evaluation of chitosan nanoformulations as potent anti-HIV therapeutic systems, Biochim Biophys Acta (2013).

  41. Chaudhary S, Bansal C, Ranga U, Singh K, Erythrodermic mycosis fungoides with hypereosinophilic syndrome: a rare presentation, Ecancermedicalscience (2013).

  42. Asokan M, Lone IN, Mukthey AB, Siddhartha P, Mariappa G, Kotehal PK, Satish B, Wilson E, Sahayam S, Velayutham G, Perumal R, Baskaran K, Rengarajan D, Muthusamy R, Philip M, Ravindra KC, Basha JN, Mizar P, Kaur G, Mehra NK, Kundu TK, Subbakrishna DK, Evident stabilization of the clinical profile in HIV/AIDS as evaluated in an open label clinical trial using a polyherbal formulation, Indian J Med Res (2013).

  43. Rao VR, Neogi U, Talboom JS, Padilla L, Rahman M, Fritz-French C, Gonzalez-Ramirez S, Verma A, Wood C, Ruprecht RM, Ranga U, Azim T, Joska J, Eugenin E, Shet A, Bimonte-Nelson H, Tyor WR, Prasad VR., Clade C HIV-1 isolates circulating in Southern Africa exhibit a greater frequency of dicysteine motif-containing Tat variants than those in Southeast Asia and cause increased neurovirulence, Retrovirology (2013).

  44. Aiyappan SK, Ranga U, Veeraiyan S, Incidentally detected isolated unilateral pulmonary artery agenesis, J Clin Diagn Res (2013).

  45. Ranga U, Aiyappan SK, Shanmugam N, Veeraiyan S, Ochronotic spondyloarthropathy, J Biol Chem (2013).

  46. Mahadevan A, Ramalingaiah AH, Parthasarathy S, Nath A, Ranga U, Krishna SS, Neuropathological correlate of the "concentric target sign" in MRI of HIV-associated cerebral toxoplasmosis, J Magn Reson Imaging (2013).

  47. Lukasz Kozubowski*^, Vikas Yadav*, Gautam Chatterjee, Shreyas Sridhar, Masashi Yamaguchi, Susumu Kawamoto, Indrani Bose, Joseph Heitman and Kaustuv Sanyal^, Ordered kinetochore assembly in the human fungal pathogen basidiomycetous yeast Cryptococcus neoformans, mBio 4(5), (2013).

  48. Rustam Ali, Sanjeev Kumar, Hemalatha Balaram and Siddhartha Sarma, Solution Nuclear Magnetic Resonance Structure of the GATase Subunit and Structural Basis of the Interaction between GATase and ATPPase Subunits in a two-subunit-type GMPS from Methanocaldococcus jannaschii, Biochemistry 52, 4308 - 4323 (2013).

  49. Uttara Chakraborty,, Aiyaz Mohamed, Pallavi Kakade, Raja Mugasimangalam, Parag P. Sadhale and Kaustuv Sanyal, A stable hybrid containing haploid genomes of two obligate diploid Candida species, Eukaryotic Cell 12, 1061 - 1071 (2013).

  50. Jitendra Thakur and Kaustuv Sanyal, Efficient neocentromere formation is suppressed by gene conversion to maintain centromere function at native physical chromosomal loci in Candida albicans, Genome Research 23, 638 - 652 (2013).

  51. Babhrubahan Roy, Neha Varshney, Vikas Yadav and Kaustuv Sanyal, The process of kinetochore assembly in yeasts, FEMS Microbiology Letters 338, 107 - 117 (2013).

  52. James P Clement, Massimiliano Aceti, Thomas K Creson, Emin D Ozkan, Yulin Shi, Nicholas J Reish, Antoine G Almonte, Brooke H Miller, Brian J Wiltgen, Courtney A Miller, Xiangmin Xu and Gavin Rumbaugh, Pathogenic SYNGAP1 mutations impair cognitive development by disrupting the maturation of dendritic spines, Cell 151, 709 - 723 (2012).

  53. Bachu M, Yalla S, Asokan M, Verma A, Neogi U, Sharma S, Murali RV, Mukthey AB, Bhatt R, Chatterjee S, Rajan RE, Cheedarla N, Yadavalli VS, Mahadevan A, Shankar SK, Rajagopalan N, Shet A, Saravanan S, Balakrishnan P, Solomon S, Vajpayee M, Satish KS, Multiple NF-κB sites in HIV-1 subtype C long terminal repeat confer superior magnitude of transcription and thereby the enhanced viral predominance, J Biol Chem (2012).

  54. Ranga U, Aiyappan SK, Veeraiyan S, Computed tomography fistulography demonstrating thyroglossal fistula: a case report, Oral Surg Oral Med Oral Pathol Oral Radiol (2012).

  55. Neogi U, Bontell I, Shet A, De Costa A, Gupta S, Diwan V, Laishram RS, Wanchu A, Ranga U, Banerjea AC, Sönnerborg A., Molecular epidemiology of HIV-1 subtypes in India: origin and evolutionary history of the predominant subtype C, PLoS One (2012).

  56. Ramana LN, Sharma S, Sethuraman S, Ranga U, Krishnan UM, Investigation on the stability of saquinavir loaded liposomes: implication on stealth, release characteristics and cytotoxicity, Int J Pharm (2012).

  57. Bachu M, Mukthey AB, Murali RV, Cheedarla N, Mahadevan A, Shankar SK, Satish KS, Kundu TK,Ranga U, Sequence insertions in the HIV type 1 subtype C viral promoter predominantly generate an additional NF-κB binding site, AIDS Res Hum Retroviruses (2012).

  58. Neogi U, Gupta S, Sahoo PN, Shet A, Rao SD, Ranga U, Prasad VR, Genetic characterization of HIV type 1 Tat exon 1 from a southern Indian clinical cohort: identification of unique epidemiological signature residues, AIDS Res Hum Retroviruses (2012).

  59. Gayatri Arun*, Vijay Akhade*, Sainitin Donakonda and M.R. Satyanarayana Rao, mrhl RNA, a long noncoding RNA, negatively regulates Wnt signaling through its protein partner Ddx5/p68 in mouse spermatogonial cells. 2012 Aug;32(15):3140-52. PMID: 22665494 (*Contributed Equally) , Molecular and Cellular Biology (2012).

  60. Jayashree Ladha*, Swati Sinha*, Vasudeva Bhat#, Sainitin Donakonda# and M.R. Satyanarayana Rao, Identification of genomic targets of transcription factor AEBP1 and its role in survival of glioma cells, Molecular Cancer Research 10, 1039 - 1051 (2012).

  61. Jitendra Thakur and Kaustuv Sanyal, A coordinated interdependent protein circuitry stabilizes the kinetochore ensemble to protect CENP-A in the human pathogenic yeast Candida albicans, PLoS Genetics 8, (2012).

  62. Kaustuv Sanyal, How do microbial pathogens make CENs?, PLoS Pathogens 8, (2012).

  63. Dehnugara Tushna, Dhar Surbhi and M.R. Satyanarayana Rao, An In Vitro, Short-Term Culture Method for Mammalian Haploid Round Spermatids Amenable for Molecular Manipulation.2012 Jan;79(1):19-30. PMID : 21953649  , Molecular Reproduction and Development (2012).

  64. Bhat, J. Y., Venkatachala, R. and Balaram, H., Substrate-induced conformational changes in Plasmodium falciparum guanosine monophosphate synthetase, FEBS J 278, 3756 - 3768 (2011).

  65. Bhat, J. Y., Venkatachala, R., Singh, K., Gupta, K., Sarma, S. P. and Balaram, H., Ammonia Channeling in Plasmodium falciparum GMP Synthetase: Investigation by NMR Spectroscopy and Biochemical Assays, Biochemistry 50, 3346 - 3356 (2011).

  66. Gadad SS, Rajan RE, Senapati P, Chatterjee S, Shandilya J, Dash PK, Ranga U, Kundu TK, HIV-1 infection induces acetylation of NPM1 that facilitates Tat localization and enhances viral transactivation, J Mol Biol (2011).

  67. Gadad SS, Senapati P, Syed SH, Rajan RE, Shandilya J, Swaminathan V, Chatterjee S, Colombo E, Dimitrov S, Pelicci PG, Ranga U, Kundu TK, The multifunctional protein nucleophosmin (NPM1) is a human linker histone H1 chaperone, Biochemistry (2011).

  68. Suparna Laha, Shankar P Das, Sujata Hajra, Kaustuv Sanyal and Pratima Sinha,   Functional characterization of the Saccharomyces cerevisiae protein Chl1 reveals the role of sister chromatid cohesion in the maintenance of spindle length during S-phase arrest.  , BMC Genetics 12, 83 (2011).

  69. Babhrubahan Roy and Kaustuv Sanyal, Diversity in Requirement of Genetic and Epigenetic Factors for Centromere Function in Fungi, Eukaryotic Cell 10, 1384 - 1395 (2011).

  70. Vinay Bulusu, Vijay Jayaraman and Hemalatha Balaram, Metabolic Fate of Fumarate, a Side Product of the Purine Salvage Pathway in the Intraerythrocytic Stages of Plasmodium falciparum, J Biol Chem 286, 9236 - 9245 (2011).

  71. Jitendra Thakur and Kaustuv Sanyal, "The essentiality of the fungus specific Dam1 complex is correlated with one kinetochore one microtubule interaction present throughout the cell cycle, independent of the nature of a centromere.", Eukaryotic Cell 10, 1295 - 1305 (2011).

  72. Babhrubahan Roy, Laura S. Burrack, Museer A. Lone, Judith Berman and Kaustuv Sanyal, "CaMtw1, a member of the evolutionarily conserved Mis12 kinetochore protein family, is required for efficient inner kinetochore assembly in the pathogenic yeast Candida albicans", Molecular Microbiology 80, 14 - 32 (2011).

  73. Liu Y, Nonnemacher MR, Stauff DL, Li L, Banerjee A, Irish B, Kilareski E, Rajagopalan N, Suchitra JB, Khan ZK, Ranga U, Wigdahl B, Structural and functional studies of CCAAT/enhancer binding sites within the human immunodeficiency virus type 1 subtype C LTR, Biomed Pharmacother (2010).

  74. Co-receptor tropism prediction among 1045 Indian HIV-1 subtype C sequences: Therapeutic implications for India, AIDS Res Ther. 7:24, (2010).

  75. Selvi RB, Krishna DV, Ostwal YB and Kundu TK, Modulators of Chromatin modifying enzymes in transcription and disease – A Connotation to Epigenetic Therapy, Biochim Biophys Acta 1799, 810 - 828 (2010).

  76. Selvi RB, Cassel JC, Kundu TK and Boutillier AL, Tuning acetylation levels with HAT activators: therapeutic strategy in neurodegenerative diseases, Biochim Biophys Acta 1799, 840 - 853 (2010).

  77. Arif M, Shandilya J, Senapati P and Kundu TK, Protein lysine acetylation in cellular function and its role in cancer manifestation, Biochim Biophys Acta 1799, 702 - 716 (2010).

  78. Arif M, Selvi BR and Kundu TK, Lysine acetylation: the tale of a modification from transcription regulation to metabolism, Chembiochem 11, 1501 - 4 (2010).

  79. Arif M, Vedamurthy BM, Choudhari R, Ostwal YB, Mantelingu K, Kodaganur GS and Kundu TK, Nitric oxide-mediated histone hyperacetylation in oral cancer: target for a water-soluble HAT inhibitor, CTK7A, Chemistry and Biology 17, 903 - 913 (2010).

  80. Ramana LN, Sethuraman S, Ranga U and Krishnan UM, Development of a liposomal nanodelivery system for nevirapine, J Biomed Sci 17 - 57 (2010).

  81. Madhavi Y, Puliyel JM, Mathew JL, Raghuram N, Phadke A, Shiva M, Srinivasan S, Paul Y, Srivastava RN, Parthasarathy A, Gupta S, Ranga U, Lakshmi VV, Joshi N, Nath I, Gulhati CM, Chatterjee P, Jain A, Priya R, Dasgupta R, Sridhar S, Dabade G, Gopakumar KM,, Abrol D, Santhosh MR, Srivastava S, Visalakshi S, Bhargava A, Sarojini NB, Sehgal D, Selvaraj S, Banerji D and , Evidence-based National Vaccine Policy, Indian J Med Res. 131, 617 - 628 (2010).

  82. Kumar GG, Mahadevan A, Guruprasad AS, Jerry M.E, Kovoor MD, P. Satishchandra, Nath A, Udaykumar Ranga and S.K. Shankar, Eccentric target sign in cerebral toxoplasmosis: neuropathological correlate to the imaging feature, J Magn Reson Imaging. 31, 1469 - 1472 (2010).

  83. Sanchari Bhattacharyya, Roshan Elizabeth Rajan, Yalla Swarupa, Ujjwal Rathore, Anjali Verma, Udaykumar Ranga and Raghavan Varadarajan, Design of a non-glycosylated outer domain derived HIV-1 gp120 immunogen that binds to CD4 and induces neutralizing antibodies, Journal of Biological Chemistry 285, 27100 - 27110 (2010).

  84. Jayashree Ladha, Sainitin Donakonda, Shipra Agrawal, Balaram Thota, M.R, Srividya, S.Sridevi, A. Arivazhagan, K. Thennarasu, Anandh Balasubramaniam, B.A. Chandramouli, A.S. Hegde, Paturu Kondaiah, Kumaravel Somasundaram, Vani Santosh and Satyanarayana MR Rao, Glioblastoma specific protein interaction network identifies PP1A and CSK21 as connecting molecules between cell cycle associated genes. 2010 Aug;70(16):6437-6447.PMID : 20663907  , Cancer Research (2010).

  85. R. Ratnapriya, J. Vijai, J. Kadandale, R. Iyer, K. Radhakrishnan and A. Anand, A locus for juvenile myoclonic epilepsy maps to 2q33-q36, Human Genetics (2010). In Press.

  86. Santosh, V.,, Arivazhagan, A.,, Sreekantha Reddy, P.,, Srinivasan ,H.,, Thota, B.,, Srividya, M.R.,, Vrinda, M.,, Sridevi, S.,, Shailaja, B.C.,, Samuel, C.,, Prasanna, K.V.,, Thennarasu, K.,, Balasubramaniam, A.,, Chandramouli, B.A.,, Hegde, .A.S.,, Somasundaram, K.,, Kondaiah, P., and Rao, M.R.S., Grade specific expression of IGFBP-2, -3 and -5 in astrocytomas: IGFBP3 emerges as a strong predictor of survival in patients with newly diagnosed glioblastoma, Cancer Epidemiology, Biomarkers and Prevention 19, 1399 - 1408 (2010).

  87. P. Sreekanthreddy, Harish Srinivasan, Durairaj Mohan Kumar, Mamatha Nijaguna, S. Sridevi, M. Vrinda, A. Arivazhagan, Anandh Balasubramaniam, A.S. Hegde, A. Chandramouli, Vani Santosh, M.R.S. Rao, Puturu Kondaiah and umaravel Somasundaram, Identification of potential serum biomarkers of glioblastoma: Serum osteopontin levels correlate with poor prognosis, Cancer Epidemiology, Biomarkers and Prevention 19, 1409 - 1422 (2010).

  88. Udaykumar Ranga, Akhil Banerjea, Sekhar Chakrabarti, Debashish Mitra., HIV/AIDS research in India-Past, Present and future, Current Science 98 , 335 - 345 (2010).

  89. Udaykumar Ranga, The Saga of the HIV Controversy: Nobel Prize in Physiology or Medicine – 2008, Resonance 14 , 472 - 498 (2010).

  90. Sreenath K, Pavithra L, Singh S, Sinha S, Dash PK, Siddappa NB, Ranga U, Mitra D, Chattopadhyay S., Nuclear Matrix protein SMAR1 represses HIV-1 LTR mediated transcription through chromatin remodeling, Virology 400, 76 - 85 (2010).

  91. Karthigeyan D, Prasad SB, Shandilya J, Agrawal S and Kundu TK, Biology of Aurora A kinase: Implications in cancer manifestation and therapy, Med Res Rev (2010). In Press.

  92. Das C, Gadad SS and Kundu TK, Human Positive Coactivator 4 Controls Heterochromatinization and Silencing of Neural Gene Expression by Interacting with REST/NRSF and CoREST, J Mol Biol 397, 1 - 12 (2010).

  93. Gadad SS, Shandilya J, Kishore AH and Kundu TK, NPM3, a member of the nucleophosmin/nucleoplasmin family, enhances activator-dependent transcription, Biochemistry 49, 1355 - 1357 (2010).

  94. Selvi BR, Batta K, Kishore AH, Mantelingu K, Varier RA, Balasubramanyam K, Pradhan SK, Dasgupta D, Sriram S, Agrawal S and Kundu TK, Identification of a Novel Inhibitor of Coactivator-associated Arginine Methyltransferase 1 (CARM1)-mediated Methylation of Histone H3 Arg-17, J Biol Chem 285, 7143 - 7152 (2010).

  95. Venu P, Chakraborty S. and Inamdar M., Analysis of long- term culture properties and pluripotent character of two sibling human embryonic stem cell lines derived from discarded embryos, In vitro Cellular & Developmental Biology - Animal 46, 200 - 205 (2010).

  96. James P Clement, Andrew D Randall and Jonathan T Brown, mGluR1 activity generates persistent, NMDA receptor-dependent, depression of hippocampal pyramidal cell excitability, European Journal of Neuroscience 12, 2347 - 2362 (2009).

  97. Chathoth KT, Ganesan G and Rao MR, Identification of a novel nucleolin related protein (NRP) gene expressed during rat spermatogenesis, BMC Mol Biol. 1, 10 - 64 (2009).

  98. Kolthur-Seetharam U, Pradeepa MM, Gupta N, Narayanaswamy R and Rao MR., Spatiotemporal organization of AT- and GC-rich DNA and their association with transition proteins TP1 and TP2 in rat condensing spermatids, J Histochem Cytochem 57, 951 - 962 (2009).

  99. Pradeepa MM,, Nikhil G,, Hari Kishore A,, Bharath GN,, Kundu TK, and Rao MR., Acetylation of transition protein 2 (TP2) by KAT3B (p300) alters its DNA condensation property and interaction with putative histone chaperone NPM3, J Biol Chem 284, 29956 - 67 (2009).

  100. Vimaleswaran KS,, Radha V,, Jayapriya MG,, Ghosh S,, Majumder PP,, Rao MR, and Mohan V., Evidence for an association with type 2 diabetes mellitus at the PPARG locus in a South Indian population, Metabolism 59, 457 - 62 (2009).

  101. Vimaleswaran KS,, Radha V,, Ghosh S,, Majumder PP,, Rao MR, and Mohan V., A Haplotype at the UCP1 Gene Locus Contributes to Genetic Risk for Type 2 Diabetes in Asian Indians (CURES-72). , Metab Syndr Relat Disord. 8, 63 - 8 (2009).

  102. Chakrabarty SP, Ramapanicker R, Mishra R, Chandrasekaran S and Balaram H, Development and characterization of lysine based tripeptide analogues as inhibitors of Sir2 activity., Bioorg Med Chem 17, 8060 - 8072 (2009).

  103. Susmita Gurjar, Anita Desai, Mangaiarkarasi A, Udaykumar Ranga, V Ravi, Molecular characterization of a full- length genome of HIV-2 isolate from India, J Acquir Immune Defic Syndr 52 , 329 - 335 (2009).

  104. Pradeepa MM, Nikhil G, Hari Kishore A, Bharath GN, Kundu TK and Rao MR, Acetylation of transition protein 2 (TP2) by KAT3B (p300) alters its DNA condensation property and interaction with putative histone chaperone NPM3, J Biol Chem 284, 29956 - 29967 (2009).

  105. Venkatesh Prasanna Kashi, Rajesh Abraham Jacob, Siddhartha Paul, Kaustuv Nayak, Soumya Swaminathan, Satish KS, Udaykumar Ranga, HIV-1 Tat-specific IgG antibodies in high-responders target a B-cell epitope in the cysteine-rich domain and block extracellular Tat efficiently Vaccine, Vaccine, 27, 6739 - 6747 (2009).

  106. Andrews et al., Consensus Guidance for Banking and Supply of Human Embryonic Stem Cell Lines for Research Purposes International Cell Banking Initiative, Stem Cell Reviews and Reports 5(4), 301 - 314 (2009).

  107. R. Ratnapriya, P. Satishchandra, S. Dilip, G. Gadre and A. Anand, Familial autosomal dominant reflex epilepsy triggered by hot water maps to 4q24-q28, Human Genetics 126, 677 - 683 (2009).

  108. R. Ratnapiya, P. Satishchandra, S. Dilip Kumar, G. Gadre, R. Reddy and A. Anand, A locus for autosomal dominant reflex epilepsy precipitated by hot water maps at chromosome 10q21.3-q22.3, Human Genetics 125, 541 - 549 (2009).

  109. Arif M, Pradhan SK, Thanuja GR, Mantelingu K, Vedamurthy M, Dasgupta D and Kundu TK, Mechanism of p300 specific histone acetyltransferase inhibition by small molecules, J Med Chem 52, 267 - 277 (2009).

  110. Ravindra KC, Selvi BR, Arif M, Reddy BA, Thanuja GR, Agrawal S, Pradhan SK, Nagashayana N, Dasgupta D and Kundu TK., Inhibition of lysine acetyltransferase KAT3B/ p300 activity by a naturally occurring, hydroxynaphthoquinone, plumbagin, J Biol Chem 284, 24453 - 24464 (2009).

  111. Shandilya J, Swaminathan V, Gadad SS, Choudhari R, Kodaganur GS and Kundu TK, Acetylated NPM1 localizes in the Nucleoplasm and Regulates Transcriptional Activation of Genes Implicated in Oral Cancer Manifestation, Mol. Cell Biol. 29, 5115 - 5127 (2009).

  112. Gadad SS, Shandilya J, Swaminathan V and Kundu TK, Histone chaperone as coactivator of chromatin transcription: Role of acetylation, Chromatin Protocols (Humana Press) 523, 263 - 278 (2009).

  113. Selvi BR and Kundu TK, Reversible acetylation of Chromatin: Implication in regulation of gene expression, disease and therapeutics, Biotechnol J 4, 375 - 390 (2009).

  114. Sharma AK, Sharma SK, Surolia A, Surolia N and Sarma SP, Solution structures of conformationally equilibrium forms of holo-acyl carrier protein (PfACP) from Plasmodium falciparum provides insight into the mechanism of activation of ACPs. Biochemistry, 45, 6904 - 6916 (2009).

  115. Karmodiya K, Surolia N, Analyses of co-operative transitions in Plasmodium falciparum beta-ketoacyl acyl carrier protein reductase upon co-factor and acyl carrier protein binding. FEBS J , 273, 4093 - 4103 (2009).

  116. Kumar G, Parasuraman P, Sharma SK, Banerjee T, Karmodiya K, Surolia N, Surolia A., Discovery of a Rhodanine Class of Compounds as Inhibitors of Plasmodium falciparum Enoyl-Acyl Carrier Protein Reductase. J Med Chem, 50, 2265 - 75 (2009).

  117. Mishra S, Karmodiya K, Parasuraman P, Surolia A, Surolia N, Design, synthesis, and application of novel triclosan prodrugs as potential antimalarial and antibacterial agents. Bioorg Med Chem, (2009). In Press.

  118. Karmodiya K, Modak R, Sahoo N, Sajad S, Surolia N, Deciphering the key residues in Plasmodium falciparum beta-ketoacyl acyl carrier protein     reductase responsible for interactions with Plasmodium falciparum acyl carrier protein. FEBS J., (2009). In Press.

  119. Banerjee T, Sharma SK, Surolia N, Surolia A,   Epigallocatechin gallate is a slow-tight binding inhibitor of enoyl-ACP reductase from Plasmodium falciparum.Biochem Biophys Res Commun, (2009). In Press.

  120. Gupta S, Modak R, Surolia N, Surolia A., Partial molar volumes of acyl carrier proteins are related to their states of acylation. Biochem Biophys Res Commun, (2009). In Press.

  121. Misra A, Surolia N, Surolia A., Catalysis and mechanism of malonyl transferase activity in type II fatty acid biosynthesis acyl carrier proteins.Mol Biosyst, (2009). In Press.

  122. Sharma S, Sharma SK, Surolia N, Surolia A, beta-Ketoacyl-ACP synthase I/II from Plasmodium falciparum (PfFabB/F)-Is it B or F? IUBMB Life.  , (2009). In Press.

  123. Pidugu LS, Maity K, Ramaswamy K, Surolia N, Suguna K, Analysis of proteins with the 'Hot dog' fold: Prediction of function and identification of catalytic residues of hypothetical proteins      , (2009). In Press.

  124. Modak R, Sinha S and Surolia N,  Isothermal unfolding studies on the apo and holo forms of Plasmodium falciparum acyl carrier protein. Role of the 4'-phosphopantetheine group in the stability of the holo form of  Plasmodium falciparum acyl carrier protein. , FEBS Journal 274, 3313 - 3326 (2009).

  125. Bulusu V, Srinivasan B, Bopanna M P and Balaram H, Elucidation of the substrate specificity, kinetic and catalytic mechanism of adenylosuccinate lyase from Plasmodium falciparum, Biochim Biophys Acta. 1794, 642 - 654 (2009).

  126. Inamdar M, Parvathy Venu, Srinivas M S, Kamini Rao and K. VijayRaghavan,   Derivation and characterization of two sibling human embryonic stem cell lines from discarded Grade III embryos, Stem Cells Dev 18(3, 423 - 433 (2009).

  127. Sunil K. Noothi, Mamata Kombrabail, Kundu T.K., G. Krishnamoorthy and Basuthkar J. Rao, Enhanced DNA dynamics due to cationic reagents, topological states of dsDNA and high mobility group box 1 as probed by PicoGreen, FEBS 276, 541 - 551 (2009).

  128. R. Selvi, S Pradhan, J Shandilya, C. Das, B S Sailaja, G. Nagashankar, S. Gadad, A Reddy, D Dasgupta and Kundu T.K., Putative anticancer therapeutic, Sanguinarine interacts with chromatin; modulates epigenetic modifications and chromatin transcription, Chem Biol., 16, 203 - 216 (2009).

  129. K. Batta, Masatoshi Yokokawa, K. Takeyasu and Kundu T.K., Human Transcriptional coactivator PC4 stimulates DNA end joining and activates DSB repair activity. JMB, J Mol Biol 385, 788 - 799 (2009). In Press.

  130. Arunima Chatterjee, R. Jalvi, Nishtha Pandey, R. Rangasayee and A. Anand, A novel locus DFNA59 for autosomal dominant nonsyndromic hearing loss maps at chromosome 11p14.2-q12.3, Human Genetics 124, 669 - 675 (2009).

  131. Reddy SP, Britto R, Vinnakota K, Aparna H, Sreepathi HK, Thota B, Kumari A, Shilpa BM, Vrinda M, Umesh S, Samuel C, Shetty M, Tandon A, Pandey P, Hegde S, Hegde AS, Balasubramaniam A, Chandramouli BA, Santosh V, Kondaiah P, Somasundaram K and Rao MR, Novel glioblastoma markers with diagnostic and prognostic value identified through transcriptome analysis, Clin Cancer Res. 14, 2978 - 2987 (2008).

  132. Reddy P.S, Umesh, S, Thota, B, Tandon, A, Pandey, P, Hegde, A.S, Balasubramaniam, A, Chandramouli, B.A, Santosh, V, Rao M.R.S, Kondaiah, P and Somasundram, K, PEBF1/NAmPRTase/Visfatin: A potential malignant astrocytoma/glioblsatoma serum marker with prognostic value, Cancer Biol Ther. 7, 663 - 668 (2008).

  133. Vimaleswaran KS, Radha V, Ramya K, Babu HN, Savitha N, Roopa V, Monalisa D, Deepa R, Ghosh S, Majumder PP, Rao MR and Mohan V, A novel association of a polymorphism in the first intron of adiponectin gene with type 2 diabetes, obesity and hypoadiponectinemia in Asian Indians, Hum Genet. 123, 599 - 605 (2008).

  134. Pradeepa MM, Manjunatha S, Sathish V, Agrawal S and Rao MR, Involvement of importin- 4 in the transport of transition protein 2 into the spermatid nucleus, Mol Cell Biol. 28, 4331 - 4341 (2008).

  135. Ganesan G and Rao SM, A novel noncoding RNA processed by Drosha is restricted to nucleus in mouse, RNA 14, 1399 - 410 (2008).

  136. Karmodiya K and Surolia N*, A unique and differential effect of denaturants on co-factor mediated activation of Plasmodium falciparum β-ketoacyl-ACP reductase. PROTEINS: Structure, Function, and Bioinformatics, 70, 528 - 538 (2008).

  137. Mishra S, Karmodiya K, Parasuraman P, Surolia A, Surolia N, Design, synthesis, and application of novel triclosan prodrugs as potential antimalarial and antibacterial agents. Bioorg Med Chem. , 16, 5536 - 5546 (2008).

  138. Mishra S, Karmodiya K, Surolia N, Surolia A., Synthesis and exploration of novel curcumin analogues as anti-malarial agents. Bioorg Med Chem. 16(6):2894-902, 16, 2894 - 2902 (2008).

  139. Gratraud, P., Surolia N., Besra, G., Surolia, A., and Kremer, L, Antimycobacterial activity and mechanism of action of NAS-91. Antimicrob Agents Chemother., 52, 1162 - 1166 (2008).

  140. Karmodiya K, Modak R, Sahoo N, Sajad S, Surolia N,     Deciphering the key residues in Plasmodium falciparum beta-ketoacyl acyl carrier protein reductase responsible for interactions with Plasmodium falciparum acyl carrier protein., FEBS Journal 275, 4756 - 66 (2008).

  141. Karmodiya K and Surolia N,  A unique and differential effect of denaturants on co-factor mediated activation of Plasmodium falciparum -ketoacyl-ACP reductase., Proteins 70, 528 - 538 (2008).

  142. Mishra S, Karmodiya K, Parasuraman P, Surolia A, Surolia N,  Design, synthesis, and application of novel triclosan prodrugs as potential antimalarial and antibacterial agents. Bioorg Med Chem. 16(10):5536-46, Bioorg Med Chem 16, 5536 - 5546 (2008).

  143. Gratraud, P., Surolia N., Besra, G., Surolia, A., and Kremer, L.,  Antimycobacterial activity and mechanism of action of NAS-91. Antimicrob Agents Chemother, Antimicrob Agents Chemother 52, 1162 - 1166 (2008).

  144. Karmodiya K, Modak R, Sahoo N, Sajad S, Surolia N, Deciphering the key residues in Plasmodium falciparum beta-ketoacyl acyl carrier protein reductase responsible for interactions with Plasmodium falciparum acyl carrier protein, FEBS Journal 275, 4756 - 4766 (2008).

  145. Mehrotra S and Balaram H, Methanocaldococcus jannaschii adenylosuccinate synthetase: Studies on temperature dependence of catalytic activity and structural stability, Biochim Biophys Acta. 1784, 2019 - 2028 (2008).

  146. Datta KKR, Srinivasan B, Balaram H and Eswaramoorthy M, Synthesis of agarose-metal/semiconductor nanoparticles having superior bacteriocidal activity and their simple conversion to metal-carbon composites, journal of chemical sciences 120, 579 - 586 (2008).

  147. Gayathri P, Sujay Subbyya IN, Ashok CS, Selvi TS, Balaram H and Murthy MRN, Crystal structure of a chimera of human and Plasmodium falciparum hypoxanthine guanine phosphoribosyltransferases provides insights into oligomerization, Proteins 73, 1010 - 1020 (2008).

  148. Chakrabarty SP, Saikumari YK, Bopanna MP and Balaram H,  Biochemical characterization of Plasmodium falciparum Sir2, a NAD+-dependent deacetylase, Molecular and Biochemical Parasitology 158, 139 - 151 (2008).

  149. Bhat JY, Shastri BG and Balaram H, Kinetic and biochemical characterization of Plasmodium falciparum GMP synthetase, Biochemical journal 409, 263 - 273 (2008).

  150. D. Das, R. Aradhya, D. Ashoka and M. Inamdar, Macromolecular uptake in Drosophila pericardial cells requires Rudhira function, Experimental Cell Research 314, 1804 - 1810 (2008).

  151. J. Dinesh, C. Deepak, S. Kavitha, M. Inamdar and M. Eswaramoorthy, Carbon spheres assisted synthesis of porous bioactive glass containing hydroxycarbonate apatite nanocrystals: A material with  high in vitro bioactivity, J. Phys. Chem. C 112, 7379 - 7384 (2008).

  152. Robyn M.B. Loureiro, Kelli-Ann Monaco, Joseph B. Kearney, Courtney E. Blickarz-Durand, Suzanne L. Kirby, Maneesha S. Inamdar and Victoria L. Bautch, CSF-1 is Required for Early Embryonic Macrophage Development: Characterization of the csfmop/csfmop Mutation in ES cell-derived Macrophages, British Journal of Hematology 141, 739 - 742 (2008).

  153. R. Selvi, D Jagadeesan, B.S. Suma, G. Nagashankar, M. Altaf, K. Balasubramanyam, M. Eswaramoorthy and Kundu T.K., Intrinsically Fluorescent Carbon Nanospheres as a Nuclear Targeting Vector: Delivery of Membrane-Impermeable Molecule to Modulate Gene Expression In Vivo, Nano lett 8, 3182 - 8 (2008).

  154. P Kumar, R. Selvi, H. A. Kishore, Kundu T.K. and C. Narayana, Surface enhanced Raman spectroscopic studies of coactivator-associated arginine methyltransferase 1., J Phys Chem B 112, 6703 - 7 (2008).

  155. H. A. Kishore, B.M. Vedamurthy, K. Mantelingu, S. Agarwal, B. A. Reddy, S. Roy, K. S. Rangappa and Kundu T.K., Specific small-molecule activator of Aurora kinase A induces autophosphorylation in a cell-free system., J Med Chem 51, 792 - 797 (2008).

  156. M. RamShankar, Aparna G, R. Jalvi, CR Srikumari Srisailapathy, V. Malhotra, S Chadha, A Agarwal, A Ramesh, R. Rangasayee and A. Anand, Functional consequences of novel connexin 26 mutations associated with hereditary hearing loss, European Journal of Human Genetics 1 - 8 (2008).

  157. A. Kapoor, P. Satishchandra, R. Ratnapriya, Ramesh Reddy, Jayaram Kadandale, Susarla K Shankar and A. Anand, An idiopathic epilepsy syndrome linked to 3q13.3-q21 and missense mutations in the extracellular calcium sensing receptor gene, Annals of Neurology 64, 158 - 167 (2008).

  158. *Sreedevi Padmanabhan, *Jitendra Thakur, Rahul Siddharthan and Kaustuv Sanyal, "Rapid evolution of Cse4p-rich centromeric DNA sequences in closely-related pathogenic yeasts, Candida albicans and Candida dubliniensis.", Proceedings of the National Academy of Sciences of the United States of America 105, 19797 - 19802 (2008).

  159. M. Mishra, S. Vetrivel, N. B. Siddappa, U. Ranga and P. Seth, Clade Specific Neurotoxicity of HIV Tat: Significance of the Dicysteine C30C31 Motif, Annals of Neurology 63, 366 - 376 (2008).

  160. D. Das, D. Ashoka, A. Rajaguru and M. S. Inamdar, Gene expression analysis in post-embryonic pericardial cells of Drosophila, Gene expression patterns 8, 199 - 205 (2008).

  161. D. Das, T. C. Rajaguru and M. S. Inamdar, Post-embryonic pericardial cells of Drosophila are required for overcoming toxic stress but not for cardiac function or adult development, Cell and Tissue Research 331, 565 - 570 (2008).

  162. Vasudev R. Rao, Andrew R. Sas, Eliseo A. Eugenin, N. B. Siddappa, Heather Bimonte-Nelson, Joan W. Berman, Ranga U, William R. Tyor and Vinayaka R Prasad,  Human Immunodeficiency Virus-1 Clade-Specific Differences in the Induction of Neuropathogenesis., J. Neurol. Sciences 28, 10010 - 16 (2008).

  163. Prashanta Kumar Dash, Nagadenahalli Byrareddy Siddappa, Asokan Mangaiarkarasi, Aruna V Mahendarkar, Padmanabhan Roshan, Krishnamurthy Kumar Anand,, Anita Mahadevan, Parthasarathy Satishchandra, Susarla K, Vinayaka R Prasad and Ranga U,  ‘Exceptional molecular and coreceptor-requirement properties of molecular clones isolated from an Human Immunodeficiency Virus Type-1 subtype-C infection’ Note: Highly accessed., Retrovirology 5 - 25 (2008).

  164. Mahadevan A, Tagore R, N. B. Siddappa, Santosh V, Yasha TC, Ranga U, Chandramouli BA and Shankar SK, Giant serpentine aneurysm of vertebrobasilar artery mimicking dolichoectasia--an unusual complication of pediatric AIDS. Report of a case with review of the literature., Clin.Neuropathol. 37 - 52 (2008).

  165. Bodhini D, Radha V, Deepa R, Ghosh S, Majumder PP, Rao MR and Mohan V, The G1057D polymorphism of IRS-2 gene and its relationship with obesity in conferring susceptibility to type 2 diabetes in Asian Indians, Int J Obes (Lond) 1, 100 - 102 (2007).

  166. Ramprasad S, Radha V, Mathias RA, Majumder PP and Rao MR, Rage gene promoter polymorphisms and diabetic retinopathy in a clinic-based population from South India, Eye (Lond) 3, 395 - 401 (2007).

  167. Pradeepa MM and Rao MR, Chromatin remodeling during mammalian spermatogenesis: role of testis specific histone variants and transition proteins, Soc Reprod Fertil Suppl 63, 1 - 10 (2007).

  168. Radha V, Vimaleswaran KS, Babu S, Deepa R, Anjana M, Ghosh S, Majumder PP, Rao MR and Mohan V, Lack of association between serum adiponectin levels and the Pro12Ala polymorphism in Asian Indians, Diabet Med. 24, 398 - 402 (2007).

  169. Gowda S, Kumaran M, Suma BS and Rao MR, Single nucleotide polymorphism analysis of the nucleotide excision repair genes XPC, XPA, and XPG in the Indian population, Hum Biol. 79, 545 - 562 (2007).

  170. Kavitha Y, Thomas S, Damodaran A, Ramakrishna L, Ranga U, Manjunath R., Replication of Japanese encephalitis virus in mouse brain induces alterations in lymphocyte response, Acta Virol., 51, 179 - 87 (2007).

  171. Ramya TN, Surolia N, Surolia A., 15-deoxyspergualin inhibits eukaryotic protein synthesis through eIF2alpha phosphorylation. Biochem J.; 401(2):411-20, 401, 411 - 421 (2007).

  172. Ramya TN, Mishra S, Karmodiya K, Surolia N, Surolia A., Inhibitors of nonhousekeeping functions of the apicoplast defy delayed death in Plasmodium falciparum. Antimicrob Agents Chemother.; 51(1):307-16, 51, 307 - 316 (2007).

  173. Sharma SK, Parasuraman P, Kumar G, Surolia N, Surolia A., Green tea catechins potentiate triclosan binding to enoyl-ACP reductase from Plasmodium falciparum (PfENR). J Med Chem.; 50(4):765-75, 50, 765 - 775 (2007).

  174. Swarnamukhi PL, Sharma SK, Padala P, Surolia N, Surolia A, Suguna K., Packing and loop-structure variations in non-isomorphous crystals of FabZ from Plasmodium falciparum. Acta Crystallogr D Biol Crystallogr; 63(Pt 4):458-64., 63, 458 - 464 (2007).

  175. Modak R, Sinha S and Surolia N, Isothermal unfolding studies on the apo and holo forms of Plasmodium falciparum acyl carrier protein. Role of the 4'-phosphopantetheine group in the stability of the holo form of Plasmodium falciparum acyl carrier protein. FEBS Journal,  , 274, 3313 - 3326 (2007).

  176. Sharma S, Sharma SK, Modak R, Karmodiya K, Surolia N, Surolia A., A mass spectrometry based systems approach for the identification of inhibitors of Plasmodium falciparum fatty acid synthase. Antimicrob Agents Chemother, 51, 2252 - 2258 (2007).

  177. Ramya TN, Karmodiya K, Surolia A, Surolia N, 15-deoxyspergualin primarily targets the trafficking of apicoplast proteins in Plasmodium falciparum.  2, Journal of Biological Chemistry 282, 6388 - 6397 (2007).

  178. Gayathri P, Balaram H and Murthy MRN, Structural biology of plasmodial proteins, current opinion in structural biology 17, 744 - 754 (2007).

  179. Mehrotra S and Balaram H,  Kinetic characterization of adenylosuccinate synthetase from the thermophilic archaea Methanocaldococcus jannaschii, Biochemistry 46, 12821 - 12832 (2007).

  180. Srinivasan B and Balaram H, ISN1 nucleotidases and HAD superfamily protein fold: in silico sequence and structure analysis, In silico Biology 7, 0019 (2007).

  181. Sabareesh V, Ranganayaki RS, Raghothama S, Bopanna MP, Balaram H, Srinivasan MC and Balaram P, Identification and characterization of a library of microheterogeneous cyclohexadepsipeptides from the fungus Isaria, journal of natural products 70, 715 - 729 (2007).

  182. G. L. Cavalleri, N. M. Walley, N. Soranzo, J. Mulley, C. P. Doherty, A. Kapoor, C. Depondt, J. M. Lynch, I. E. Scheffer, A. Heils, A. Gehrmann, P. Kinirons, S. Gandhi, P. Satishchandra, N. W. Wood, A. Anand, T. Sander, S. F. Berkovic, N. Delanty, D. B. Goldstein and S. M. Sisodiya, A multicenter study of BRD2 as a risk factor for Juvenile Myoclonic Epilepsy, Epilepsia 48, 706 - 712 (2007).

  183. G. S. Shekhwat, M. Ramshankar, R. Jalvi, R. Rangasayee and A. Anand, Implications of disclosing auditory genetic mutation to a family: A case study, International Journal of Audiology 46, 384 - 387 (2007).

  184. G. V. Pavan Kumar, S. Sruthi, B. Vibha, B. A. Ashok Reddy, T. K. Kundu and N. Chandrabhas, Hot spots in Ag core-Au shell nanoparticles potent for surface enhanced Raman scattering studies of biomolecules, J Phys Chem. C 111, 4388 - 4392 (2007).

  185. A. Mahadevan, S. K. Shankar, P. Satishchandra, U. Ranga, Y. T. Chickabssavaiah, S. Vani V. Ravi, C. A. Pardo, A. Nath and M. C. Zink, Characterization of Human Immunodeficiency Virus (HIV)-Infected Cells in Infiltrates Associated With CNS Opportunistic Infections in Patients With HIV Clade C Infection, Neuropathology&Experimental Neurology 66, 799 - 808 (2007).

  186. U. Ranga and P. Venkatesh, The HIV-1 Genome: a possible target for control?, HIV/AIDS 153 - 161 (2007).

  187. K. Batta and Kundu T.K., Activation of p53 function by human transcriptional coactivator PC4: role of protein-protein interaction, DNA bending, and posttranslational modifications, Mol. Cell Biol. 27, 7603 - 7614 (2007).

  188. M. Arif, G. V. Kumar, C. Narayana and Kundu T.K., Autoacetylation induced specific structural changes in histone acetyltransferase domain of p300: probed by surface enhanced Raman spectroscopy, J Phys Chem. B 111, 11877 - 9 (2007).

  189. A. Kapoor, R. Ratnapriya, G Kuruttukulam and A. Anand, A novel genetic locus for juvenile myoclonic epilepsy at chromosome 5q12-q14, Human Genetics 121, 655 - 662 (2007).

  190. K. Siva, K. Gokul and M. S. Inamdar, Expression of conserved siganaling pathway genes during spontaneous vascular differentiation of R1 embryonic stem cells and in Py-4-1 endothelial cells, Journal of Biosciences 32, 1291 - 1298 (2007).

  191. K. Mantelingu, B. A. Reddy, V. Swaminathan, A. H. Kishore, N. B. Siddappa, G. V. Kumar, G. Nagashankar, N. Natesh, S. Roy, P. P. Sadhale, U. Ranga, C. Narayana and T. K. Kundu, Specific Inhibition of p300-HAT Alters Global Gene Expression andRepresses HIV Replication, Chemistry and Biology 14, 645 - 657 (2007).

  192. N. B. Siddappa, V. P. Kashi, M. Venkatramanan, A. Balasiddaiah, N. Jayasuryan, A. Mahadevan, A. Desai, K. S. Satish, S. K. Shankar, V. Ravi and U. Ranga, Gene Expression Analysis from Human Immunodeficiency Virus Type 1 Subtype C Promoter and Construction of Bicistronic Reporter Vectors, AIDS Research and Human Retroviruses 23, 1268 - 1278 (2007).

  193. N. B. Siddappa, A. Avinash, M. Vekataramanan and U. Ranga, Regeneration of commercial nucleic acid extraction columns without the risk of carryover contamination, BioTechniques 42, 186 - 192 (2007).

  194. K. Siva, V. Parvathy, A. Mahadevan, S. K. Shankar and M. S. Inamdar, Human BCAS3 expression in embryonic stem cells and vascular precursors suggests a role in human embryogenesis and tumor angiogenesis, PLoS ONE 2, (2007).

  195. A. H. Kishore, K. Batta, C. Das, S. Agarwal and Kundu T.K., p53 regulates its own activator - Transcriptional coactivator PC4; A new p53 responsive gene, Biochem J 406, 437 - 444 (2007).

  196. K. Mantelingu, B. A. Reddy, V. Swaminathan, A. H. Kishore, N. B. Siddappa, G. V. Kumar, G. Nagashankar, N. Natesh, S. Roy, P. P. Sadhale, U. Ranga, C. Narayana and Kundu T.K., Specific Inhibition of p300-HAT Alters Global Gene Expression and Represses HIV replication, Chem. Biol. 14, 645 - 657 (2007).

  197. V. Swaminathan, B. A. Reddy, R. Selvi, M. S. Sukanya and Kundu T.K., Small Molecule Modulators in Epigenetics: Impications in Gene Expression and Therapeutics, Subcell Biochem 41, 397 - 428 (2007).

  198. K. Batta, C. Das, S. S. Gadad, J. Shadilya and Kundu T.K., Reversible Acetylation of Nonhistone Protiens: Role in Cellular function and Disease, Subcell Biochem 41, 193 - 214 (2007).

  199. J. Shandilya, S. Gadad, V. Swaminathan and Kundu T.K., Histone Chaperones in Chromatin Dynamics: Implication in Disease Manifestation, Subcell Biochem 41, 111 - 124 (2007).

  200. K. Mantelingu, A. H. Kishore, K. Balasubramanyam, G. V. Kumar, M. Altaf, S. N. Swamy, R. Selvi, C. Das, C. Narayana, K. S. Rangappa and Kundu T.K., Activation of p300 Histone Acetyltransferase by Small Molecules Altering Enzyme Structure: probed by Surface-Enhanced Raman Spectroscopy, J Phys Chem. B 111, 4527 - 4534 (2007).

  201. G. V. Kumar, S. Shruthi, B. Vibha, B. A. Reddy, Kundu T.K. and C. Narayana, Potent for Surface-Enhanced Raman Scattering Studies of Biomolecules, J Phys Chem. C 111, 4388 - 4392 (2007).

  202. Raghav Rajan, James P Clement and Upinder S Bhalla, Rats smell in stereo, Science 311, 666 - 670 (2006).

  203. Nishant KT, Kumar C and Rao MR, HUMHOT: a database of human meiotic recombination hot spots, Nucleic Acids Res 34, 25 - 8 (2006).

  204. Nishant KT and Rao MR, Molecular features of meiotic recombination hot spots, Bioessays 28, 45 - 56 (2006).

  205. Radha V, Vimaleswaran KS, Babu HN, Abate N, Chandalia M, Satija P, Grundy SM, Ghosh S, Majumder PP, Deepa R, Rao SM and Mohan V, Role of genetic polymorphism peroxisome proliferator-activated receptor-gamma2 Pro12Ala on ethnic susceptibility to diabetes in South-Asian and Caucasian subjects: Evidence for heterogeneity, Diabetes Care 29, 1046 - 51 (2006).

  206. Vimaleswaran KS, Radha V, Anjana M, Deepa R, Ghosh S, Majumder PP, Rao MR and Mohan V, Effect of polymorphisms in the PPARGC1A gene on body fat in Asian Indians, Int J Obes 30, 884 - 891 (2006).

  207. Ramesh S, Bharath MM, Chandra NR and Rao MR, A K52Q substitution in the globular domain of histone H1t modulates its nucleosome binding properties, FEBS Lett. 580, 5999 - 6006 (2006).

  208. Shipra A, Chetan K and Rao MR, CREMOFAC--a database of chromatin remodeling factors, Bioinformatics 22, 2940 - 2944 (2006).

  209. Kesavulu MM, Prakasha Gowda AS, Ramya TN, Surolia N, Suguna K., Plasmepsin inhibitors: design, synthesis, inhibitory studies and crystal structure analysis. J Pept Res.  , 66, 211 - 219 (2006).

  210. Swarnamukhi PL, Sharma SK, Bajaj P, Surolia N, Surolia A, Suguna K., Crystal structure of dimeric FabZ of Plasmodium falciparum reveals conformational switching to active hexamers by peptide flips. FEBS Lett ., 580, 2653 - 2660 (2006).

  211. Ramya TN, Surolia N, Surolia A., 15-Deoxyspergualin modulates Plasmodium falciparum heat shock protein function. Biochem Biophys Res Commun.; 348(2):585-92, 348, 585 - 592 (2006).

  212. Sanjay Kumar, Gyanendra Kumar, Mili Kapoor, Surolia A and Namita Surolia, Synthesis and Evaluation of Substituted Pyrazoles:  Potential Antimalarials Targeting the Enoyl-ACP Reductase of Plasmodium falciparum, Synthetic Communications; 36, 215-226, 36, 215 - 226 (2006).

  213. Ramya TN, Surolia N, Surolia A.,   Polyamine synthesis and salvage pathways in the malaria parasite Plasmodium falciparum. Biochem Biophys Res Commun.; 348(2):579-84., 348, 579 - 584 (2006).

  214. Chhibber M, Kumar G, Parasuraman P, Ramya TN, Surolia N, Surolia A., Novel diphenyl ethers: design, docking studies, synthesis and inhibition of enoyl ACP reductase of Plasmodium falciparum and Escherichia coli. Bioorg Med Chem.; 14(23):8086-98, 14, 8086 - 8098 (2006).

  215. A. Mahadevan, P. Satishchandra, K. K. Prachet, N. B. Siddappa, U. Ranga, V. Santosh, T. C. Yasha, A. Desai, V. Ravi and S. K. Shankar, Optic nerve axonal pathology is related to abnormal visual evoked responses in AIDS, Acta Neuropathologica (Berlin) 112, 461 - 469 (2006).

  216. N. B. Siddappa, M. Venkatramanan, P. Venkatesh, N. Jayasuryan, A. Desai, V. Ravi and U. Ranga, Transactivation and signaling functions of Tat are not correlated: biological and immunological characterization of HIV-1 subtype-C Tat protein, Retrovirology 3, 53 - 0 (2006).

  217. K. Siva, D. Das, A. Mukhopadhyay and M. S. Inamdar, Comparitive vascular biology: A more comprehensive approach to the analysis of circulatory system development, Journal of the Indian Institute of Science 86, 763 - 772 (2006).

  218. K. Siva and M. S. Inamdar, Rudhira is a cytoplasmic WD40 protein expressed in mouse embryonic stem cells and during embryonic erythropoiesis, Mechanisms of Development- Gene expression patterns 6, 225 - 234 (2006).

  219. C. Das, K. Hizume, K. Batta, B. R. Kumar, S. S. Gadad, S. Ganguly, S. Lorain, A. Verreault, P. P. Sadhale, K. Takeyasu and Kundu T.K., Transcriptional coactivator PC4, a chromatin-associated protein, induces chromatin condensation, Mol Cell Biol 26, 8303 - 8315 (2006).

  220. G. V. Kumar, B. A. Reddy, M. Arif, Kundu T.K. and C. Narayana, Surface-enhanced Raman scattering studies of human transcriptional coactivator p300, J Phys Chem. B 110, 16787 - 16792 (2006).

  221. R. A. Varier and Kundu T.K., Chromatin Modifications (Acetylation/ Deacetylation/ Methylation) as new targets for HIV therapy, Curr Pharm Des 12, 1975 (2006).

  222. *Baum M., *Sanyal K., P. K. Mishra, N. Thaler and J. Carbon, "Formation of functional centromeric chromatin is specified epigenetically in Candida albicans.", Proceedings of the National Academy of Sciences of the United States of America 103, 14877 - 14882 (2006).

  223. Somasundaram K, Reddy SP, Vinnakota K, Britto R, Subbarayan M, Nambiar S, Hebbar A, Samuel C, Shetty M, Sreepathi HK, Santosh V, Hegde AS, Hegde S, Kondaiah P and Rao MR, Upregulation of ASCL1 and inhibition of Notch signaling pathway characterize progressive astrocytoma, Oncogene 24, 7073 - 83 (2005).

  224. Vimaleswaran KS, Radha V, Ghosh S, Majumder PP, Deepa R, Babu HN, Rao MR and Mohan V, Peroxisome proliferator-activated receptor-gamma co-activator-1alpha (PGC-1alpha) gene polymorphisms and their relationship to Type 2 diabetes in Asian Indians, Diabet Med 22, 1516 - 21 (2005).

  225. Sharma SK, Modak R, Sharma S, Sharma AK, Sarma SP, Surolia A, Surolia N ., A novel approach for over-expression, characterization, and isotopic enrichment of a homogeneous species of acyl carrier protein from Plasmodium falciparum. Biochem Biophys Res Commun, 330, 1019 - 1026 (2005).

  226. Karmodiya K, Srivastav RK, Surolia N., Production and purification of refolded recombinant Plasmodium falciparum beta-ketoacyl-ACP reductase from inclusion bodies. Protein Expr Purif.; 42(1):131-6, 42, 131 - 136 (2005).

  227. Ramya TN, Surolia N, Surolia A., Is the fatty acid synthesis pathway a good target for anti-malarial therapy? IUBMB Life. , 57, 371 - 373 (2005).

  228. Sharma AK, Sharma SK, Surolia N, Sarma SP., NMR assignment of the Holo-ACP from malaria parasite Plasmodium Falciparum. J Biomol NMR., 32, 260 - 272 (2005).

  229. Bhor VM, Thomas CJ, Surolia N, Surolia A., Polymyxin B: an ode to an old antidote for endotoxic shock. Mol Biosyst. 2005     ) , 01, 213 - 222 (2005).

  230. H. M. Ravishankar, A Kishore and A. Anand, Mutational screening of the Parkin gene among South Indians with early onset Parkinson's disease, Journal of Neurology, Neurosurgery and Psychiatry 76, 1588 - 1590 (2005).

  231. J. Vijai, A. Kapoor, H. M. Ravishankar, P. J. Cherian, G Kuruttukulam, B. Rajendran, R Sridharan, G. Rangan, A. S. Girija, S. Jayalakshmi, S. Mohandas, K. S. Mani and A. Anand, Protective and susceptibility effects of hSKCa3 allelic variants on juvenile myoclonic epilepsy, Journal of Medical Genetics 42, 439 - 442 (2005).

  232. N. B. Siddappa, P. K. Dash, A. Mahadevan, A. Desai, N. Jayasuryan, V. Ravi, P. Satishchandra, S. K. Shankar and U. Ranga, Identification of unique B/C recombinant strains of HIV-1 in the Southern State of Karnataka, India, AIDS 19, 1426 - 1429 (2005).

  233. S. K. Shankar, A. Mahadevan, P. Satishchandra, U. Ranga, T. C. Yasha, V. Santosh, A. Chandramuki, V. Ravi and A. Nath, Neuropathology of HIV/AIDS with an overview of the Indian scene, Indian Journal of Medical Research 121, 468 - 488 (2005).

  234. N. B. Siddappa, P. K. Dash, A. Mahadevan, A. Desai, N. Jayasuryan, V. Ravi, P. Satishchandra, S. K. Shankar and U. Ranga, Identification of unique B/C recombinant strains of HIV-1 in the Southern State of Karnataka, India, AIDS 19, 1426 - 1429 (2005).

  235. Shravanthi Rampalli, L. Pavitha, Altaf Bhatt, Kundu T.K. and Samit Chattopadhay, Tumor Suppressor SMAR1 mediates Cyclin D1 Repression by Recruitment of the SIN3/Histone Deacetylase 1 complex, Mol Cell Biol 25, 8415 - 8429 (2005).

  236. V. Swaminathan, H. A. Kishore, K. K. Febitha and Kundu T.K., Human Histone Chaperone Nucleophosmin Enhances Acetylation Dependent Chromatin Transcription, Mol Cell Biol 25, 7534 - 7545 (2005).

  237. C. Das and Kundu T.K., Transcriptional regulation by the acetylation of nonhistone proteins in humans- a new target for therapeutics, IUBMB Life 57, 137 - 149 (2005).

  238. S. M. Davidson, P. A. Townsend, C. Carroll, A. Yurek-George, K. Balasubramanyam, T. K. Kundu, A. Stephanou, G. Packham, A. Ganesan and D. S. Latchman, The transcriptional coactivator p300 plays a critical role in the hypertrophic and protective pathways induced by phenylephrine in cardiac cells but is specific to the hypertrophic effect of urocortin, Chembiochem 6, 162 - 170 (2005).

  239. S. Sadasivam, S. Gupta, V. Radha, K. Batta, Kundu T.K. and G. Swarup, Caspase-1 activator 1paf is a p53- inducible gene involved in apoptosis, Oncogene 24, 627 - 636 (2005).

  240. Devgan V, Rao MR and Seshagiri PB, Impact of embryonic expression of enhanced green fluorescent protein on early mouse development, Biochem Biophys Res Commun 313, 1030 - 1036 (2004).

  241. Nishant KT, Ravishankar H and Rao MR, Characterization of a mouse recombination hot spot locus encoding a novel non-protein-coding RNA, Mol Cell Biol 12, 5620 - 5634 (2004).

  242. Lakshmi Swarna Mukhi P, Kumar Sharma S, Kapoor M, Surolia N, Surolia A, Suguna K., Crystallization and preliminary crystallographic analysis of beta-hydroxyacyl ACP dehydratase (FabZ) from Plasmodium falciparum. Acta Crystallogr D Biol Crystallogr.; 60(Pt 1):120-1, 60, 120 - 121 (2004).

  243. Kapoor M, Reddy CC, Krishnasastry MV, Surolia N, Surolia A.,   Slow-tight-binding inhibition of enoyl-acyl carrier protein reductase from Plasmodium falciparum by triclosan. Biochem J. 2004 Aug 1; 381(Pt 3):719-24, 381, 719 - 724 (2004).

  244. Kapoor M, Gopalakrishnapai J, Surolia N,* Surolia A., Mutational analysis of the triclosan-binding region of enoyl-ACP (acyl-carrier protein) reductase from Plasmodium falciparum. Biochem J.; 381(Pt 3):735-41, 381, 735 - 741 (2004).

  245. Kapoor M, Mukhi PL, Surolia N,* Suguna K, Surolia A., Kinetic and structural analysis of the increased affinity of enoyl-ACP (acyl-carrier protein) reductase for triclosan in the presence of NAD+. Biochem J.; 381(Pt 3):725-33, 381, 725 - 733 (2004).

  246. Kapoor M, Gopalakrishnapai J, Surolia N,* Surolia A., Mutational analysis of the triclosan-binding region of enoyl-ACP (acyl-carrier protein) reductase from Plasmodium falciparum. Biochem J.; 381(Pt 3):735-41, 381, 735 - 741 (2004).

  247. Pidugu LS, Kapoor M, Surolia N, Surolia A, Suguna K., Structural basis for the variation in triclosan affinity to enoyl reductases. J Mol Biol.; 343(1):147-55, 343, 147 - 55 (2004).

  248. Surolia A, Ramya TN, Ramya V, Surolia N, FAS't inhibition of malaria, Biochemical Journal 383, 401 - 412 (2004).

  249. K. Balasubramanyam, R. A. Varier, M. Altaf, V. Swaminathan, N. B. Siddappa, U. Ranga and T. K. Kundu, Curcumin, a novel p300/CBP-specific inhibitor of acetyltransferase, represses the acetylation of histones/nonhistones proteins and histone acetyltransferase-dependent chromatin transcription, Journal of Biological Chemistry 279, 51163 - 51171 (2004).

  250. L. Ramakrishna, K. K. Anand, K. M. Mohankumar and U. Ranga, Codon optimization of an inherently non-immunodominant HIV-1 antigen generates strong immune responses in mice following genetic immunization, Journal of Virology 78, 9174 - 9189 (2004).

  251. N. B. Siddappa, P. K. Dash, J. Narayana, A. Mahadevan, B. Hoffman, R. Keefe, K. S. Satish, B. Satish, K. Sreekanthan, K. Venu, P. Satishchandra, V. Ravi, S. K. Shankar, R. Shankarappa and U. Ranga, Identification of Subtype C Human Immunodeficiency Virus Type 1 by Subtype-Specific Polymerase Chain Reaction and Its Use in the Characterization of Viruses Circulating in the Southern Parts of India, Journal of Clinical Microbiology 42, 2742 - 2751 (2004).

  252. S. Sinha, T. Mathews, G. R. Arunodaya, N. B. Siddappa, U. Ranga, A. Desai, V. Ravi and A. B. Tally, HIV-1 clade C associated ALS-like disorder: First report from India, Journal of the Neurological Sciences 224, 97 - 100 (2004).

  253. L. Ramakrishna, K. K. Anand, M. Mahalingam, K. M. Mohankumar, R. Shilpa, N. B. Siddappa and U. Ranga, Codon optimization and ubiquitin conjugation of Human Immunodeficiency Virus-1 Tat lead to enhanced cell-mediated immune responses, Vaccine 22, 2586 - 2598 (2004).

  254. U. Ranga, R. Shankarappa, N. B. Siddappa, R. Lakshmi, R. Nagendran, M. Mahalingam, A. Mahadevan, J. Narayana, P. Satishchandra, S. K. Shankar and V. R. Prasad, Tat protein of Human Immunodeficiency Virus Type-1 subtype C viruses is a defective chemokine, Journal of Virology 78, 2586 - 2590 (2004).

  255. K. Balasubramanyam, R. A. Varier, M. Altaf, V. Swaminathan, N. B. Siddappa, U. Ranga and Kundu T.K., Curcumin, a novel p300/CBP specific inhibitor of acetyltransferase, represses the acetylation of histones/nonhistone proteins and HAT dependent chromatin transcription, J Biol Chem 279, 51163 - 51171 (2004).

  256. K. Balasubramanyam, M. Altaf, A. V. Radhika, V. Swaminathan, A. Ravindran, P. P. Sadhale and Kundu T.K., Polyisoprenylated benzophenone, garcinol, a natural HAT inhibitor represses chromatin transcription and alters global gene expression, J Biol Chem 279, 33716 - 33726 (2004).

  257. H. A. Kishore and Kundu T.K., Transcription Through Chromatin- Link to Diseases and Therapeutics, Resonance 9, 23 - 38 (2004).

  258. R. A. Varier, V. Swaminathan, K. Balasubramanyam and Kundu T.K., Implications of small molecule activator and inhibitors of histone acetyltransferases in chromatin therapy, Biochem Pharmacol 68, 1215 - 1220 (2004).

  259. S. Banerjee, B. R. Prashanth Kumar and Kundu T.K., General Transcriptional Coactivator PC4 activates p53 function, Mol Cell Biol 24, 2052 - 2062 (2004).

  260. R. Jayalakshmi and H. Balaram, Nucleotide metabolism in Plasmodium falciparum: recent developments, Medicinal Chemistry Reviews 1, 465 - 473 (2004).

  261. R. Jayalakshmi, Sonali Mehrotra, Ranjith P. Anand and H. Balaram, Unique kinetic mechanism of Plasmodium falciparum adenylosuccinate synthetase, Molecular and Biochemical Parasitology 138, 1 - 8 (2004).

  262. R. Jayalakshmi, K. Sumathy, R. P. Anand and H. Balaram, A non-active site mutation in human hypoxanthine guanine phosphoribosyltransferase expands substrate specificity, Archives of Biochemistry and Biophysics 427, 116 - 122 (2004).

  263. K. Eaazhisai, R. Jayalakshmi, P. Gayathri, R. P. Anand, K. Sumathy, H. Balaram and M. R. N. Murthy, Crystal structure of fully-ligated adenylosuccinate synthetase from Plasmodium falciparum, Journal of Molecular Biology 335, 1251 - 1264 (2004).

  264. K. Sanyal, M. Baum and J. Carbon, "Centromeric DNA sequences in the pathogenic yeast Candida albicans are all different and unique.", Proceedings of the National Academy of Sciences of the United States of America 101, 11374 - 11379 (2004).

  265. Devgan V, Thomas M, Ullas KS, Rao MR and Seshagiri PB, Embryo culture-based generation of enhanced green fluorescent protein-transgenic mice, Biochem Biophys Res Commun 303, 994 - 999 (2003).

  266. Bharath MM, Chandra NR and Rao MR, Molecular modeling of the chromatosome particle, Nucleic Acids Res 31, 4264 - 4274 (2003).

  267. Ullas KS and Rao MR, Phosphorylation of rat spermatidal protein TP2 by sperm-specific protein kinase A and modulation of its transport into the haploid nucleus, J Biol Chem 278, 52673 - 52680 (2003).

  268. Q. Saleem, S. Roy, U. Murgood, R. Saxena, I. C. Verma, A. Anand, U. Muthane, S. Jain and S. K. Brahmachari, Molecular analysis of Huntington's disease and linked polymorphisms in the Indian population, Acta Neurol. Scand. 108, 281 - 286 (2003).

  269. Ravi Vijaya Satya, Amer Mukherjee and Udaykumar Ranga, A Pattern Matching Algorithm for Codon Optimization and CpG Motif-Engineering in DNA Expression Vectors, IEEE Conference proceedings 294 (2003).

  270. A. Mukhopadhyay, D. Das and M. S. Inamdar, ES cell and tissue-specific expression of a novel conserved gene, asrij, Developmental Dynamics 227, 578 - 586 (2003).

  271. S. K. Shankar, P. Satishchandra, A. Mahadevan, A. Nalini, U. Ranga, S. Vani, T. C. Yasha and V. Ravi, Neurological Disorders Associated with HIV/AIDS: Asian Perspective, Journal of Neurovirology 9, 13 - 14 (2003).

  272. A. Mukhopadhyay, D. Das and M. S. Inamdar, ES cell and tissue-specific expression of a novel conserved gene, asrij, Developmental Dynamics 227, 578 - 586 (2003).

  273. M. S. Inamdar, Drosophila asrij is expressed in pole cells, trachea and hemocytes, Development, Genes and Evolution 213, 134 - 137 (2003).

  274. K. Balasubramanyam, V. Swaminathan, A. Ranganathan and Kundu T.K., Small Molecule Modulators of Histone Acetyltransferase p300, J Biol Chem 278, 19134 - 19140 (2003).

  275. H. A. Kishore and Kundu T.K., Transcription through chromatin ? Dynamic organization of genes, Resonance 8, 78 - 93 (2003).

  276. S. Banerjee and Kundu T.K., The acidic C-terminal domain and A-box of HMG-1 regulates p53-mediated transcription, Nucleic Acids Res 31, 3236 - 3247 (2003).

  277. S. Parthasarathy, K. Eaazhisai, H. Balaram, P. Balaram and M. R. N. Murthy, Structure of Plasmodium falciparum TIM-2-phosphoglycerate complex at 1.1A resolution, Journal of Biological Chemistry 278, 52461 - 52470 (2003).

  278. H. N. Gopi, G. Ravindra, P. P. Pal, P. Pattanaik, H. Balaram and P. Balaram, Proteolytic stability of beta-peptide bonds probed using quenched fluorescent substrates incorporating a hemoglobin cleavage site, FEBS Letters 535, 175 - 178 (2003).

  279. P. Pattanaik, G. Ravindra, C. Sengupta, K. Maithal, P. Balaram and H. Balaram, Unusual fluorescence of W168 in Plasmodium falciparum triosephosphate isomerase, probed by single-tryptophan mutants, European Journal of Biochemistry 270, 745 - 756 (2003).

  280. P. Pattanaik, B. Jain, G. Ravindra, H. N. Gopi, P. P. Pal, H. Balaram and P. Balaram, Stage specific profiling of Plasmodium falciparum proteases using an internally quenched multispecificity protease substrate, Biochemical and Biophysics Research Communications 309, 974 - 979 (2003).

  281. J. Vijai, A. Kapoor, H. M .Ravishankar, P. J. Cherian, A. S. Girija, B. Rajendran, G. Rangan, S. Jayalakshmi, S. Mohandas, K. Radhakrishnan and A. Anand, Genetic association analysis of KCNQ3 and juvenile myoclonic epilepsy in a South Indian population, Human Genetics 113, 461 - 463 (2003).

  282. A. Kapoor, J. Vijai, H. M. Ravishankar, P. Satishchandra, K. Radhakrishnan and A. Anand, Absence of Ala322Asp, a GABRA1 mutation in Juvenile Myoclonic Epilepsy families from South India, Journal of Genetics 82, 17 - 21 (2003).

  283. M. RamShankar, S. Girirajan, O. Dagan, H. M. Ravi Shankar, R. Jalvi, R. Rangasayee, K. B. Avraham and A. Anand, Contribution of connexin 26 (GJB2) mutations and founder effect to non-syndromic hearing loss in India, Journal of Medical Genetics 40, (2003).

  284. J. Vijai, P. J. Cherian, P. N. Sylaja, A. Anand and K. Radhakrishnan, Clinical characteristics of a South Indian cohort of juvenile myoclonic epilepsy probands, Seizure 12, 490 - 496 (2003).

  285. Meetei AR, Ullas KS, Vasupradha V and Rao MR, Involvement of protein kinase A in the phosphorylation of spermatidal protein TP2 and its effect on DNA condensation, Biochemistry 41, 185 - 195 (2002).

  286. Bharath MM, Ramesh S, Chandra NR and Rao MR, Identification of a 34 amino acid stretch within the C-terminus of histone H1 as the DNA-condensing domain by site-directed mutagenesis, Biochemistry 41, 7617 - 7627 (2002).

  287. Bharath MM, Chandra NR and Rao MR, Prediction of an HMG-box fold in the C-terminal domain of histone H1: insights into its role in DNA condensation, Proteins 49, 71 - 81 (2002).

  288. Haldar D, Acharya S and Rao MR, A novel structure-specific endonuclease activity associated with polypyrimidine-tract binding (PTB) related protein from rat testis, Biochemistry 41, 11628 - 11641 (2002).

  289. O. Mukherjee, Q Saleem, A. Anand, S. K. Brahmachari and S. Jain, Common psychiatric diseases and human genetic variation, Community Genetics 5, 171 - 177 (2002).

  290. U. Ranga, Human Immunodeficiency Virus-1 subtypes: Could genetic diversity translate to differential pathogenesis?, Journal of the Indian Institute of Sciences 82, 73 - 91 (2002).

  291. M. S. Inamdar, Stem cell identity: life is plastic, its fantastic!, Journal of Biosciences 27, 93 - 95 (2002).

  292. S. Kar, K. Sakaguchi, Y. Shimohigashi, S. Samaddar, R. Banerjee, G. Basu, V. Swaminathan, Kundu T.K. and S. Roy, Effect of Phosphorylation on the Structure and Fold of Transactivation domain of p53, J Biol Chem 277, 15579 - 15585 (2002).

  293. Kapil Maithal, G. Ravindra, G. Nagaraj, S. Kumar Singh, H. Balaram and P. Balaram, Subunit interface mutation disrupting an aromatic cluster in Plasmodium falciparum triosephosphate isomerase: effect on dimer stability, Protein Engineering 15, 575 - 584 (2002).

  294. I. N. Sujay Subbayya and H. Balaram, A Point mutation at the subunit interface of hypoxanthine-guanine-xanthine phosphoribosyltransferase impairs activity: Role of oligomerization in catalysis, FEBS Letters 521, 72 - 76 (2002).

  295. P. Pattanaik, R. Jayalakshmi and H. Balaram, Perspectives in drug design against malaria, Current Topics in Medicinal Chemistry 2, 483 - 505 (2002).

  296. R. Jayalakshmi, K. Sumathy and H. Balaram, Purification and characterization of recombinant Plasmodium falciparum adenylosuccinate synthetase expressed in Escherichia coli, Protein Expression and Purification 25, 65 - 72 (2002).

  297. K. Sanyal and J. Carbon, "The CENP-A homolog CaCse4p in the pathogenic yeast Candida albicans in a centromere protein essential for chromosomes transmission.", Proceedings of the National Academy of Sciences of the United States of America 99, 12969 - 12974 (2002).

  298. A. Anand, A Villella, LC Ryner, T. Carlos, SF Goodwin, HJ Song, DA Gailey, A Morles, JC Hall, BS Baker and BJ Taylor, Molecular dissection of the sex-specific and vital functions of the Drosophila melanogaster sex determination gene fruitless, Genetics 158, 1569 - 1595 (2001).

  299. Surolia N,* Surolia A., Triclosan offers protection against blood stages of malaria by inhibiting enoyl-ACP   reductase of Plasmodium falciparum, Nature Medicine 7(2), 167 - 173 (2001).

  300. K. J. Sheikh, D. Naveen, T. Sherrin, A. Murthy, K. Thennarasu, A. Anand, V. Benegal and S. Jain, Polymorphisms at the DRD2 locus in early onset alcoholism in the Indian population, Addication Biology 6, 331 - 335 (2001).

  301. Q. Saleem, A. Anand, S. K. Brahmachari, S. Jain and U. Muthane, A clinical study of patients with genetically confirmed Huntington's disease from India, J. Neurological Sciences 15, 73 - 78 (2001).

  302. Q Saleem, A. Anand, S. Jain and S. K. Brahmachari, The polyglutamine motif is highly conserved at the Clock locus in various organisms and is not polymorphic in humans, Human Genetics 109, 136 - 142 (2001).

  303. Ranga U, Defining priorities for India. Express Pharma Pulse, HIV/AIDS 28 (2001).

  304. M. S. Inamdar, Functional genomics the old fashioned way: chemical mutagenesis in mice, Bioessays 23, 116 - 120 (2001).

  305. B. R. Kumar, V. Swaminathan, S. Banerjee and Kundu T.K., p300-mediated acetylation of human ranscriptional coactivator PC4 is inhibited by phosphorylation, J Biol Chem 276, 16804 - 16809 (2001).

  306. S. K. Singh, K. Maithal, H. Balaram and P. Balaram, Synthetic peptides as inactivators of multimeric enzymes: inhibition of Plasmodium falciparum triosephosphate isomerase by interface peptides, FEBS Letters 501, 19 - 23 (2001).

  307. G. Nagaraj, M.V.Uma, M. S. Shivayogi and H. Balaram, Antimalarial activities of peptide antibiotics isolated from fungi, Antimicrobial Agents and Chemotherapy 45, 145 - 149 (2001).

  308. K. Shivashankar, I. N. S. Subbayya and H. Balaram, Development of a bacterial screen for novel hypoxanthine-guanine phosphoribosyltransferase substrates, Journal of Molecular Microbiology and Biotechnology 3, 557 - 662 (2001).

  309. S. K. Ghosh, A. Poddar, S. Hajra, K. Sanyal and P. Sinha, "The IML3/MCM19 gene of Saccharomyces cerevisiae is required for a kinetochore-related process during chromosome segregation.", Molecular Genetics and Genomics 265, 249 - 257 (2001).

  310. Q. Saleem, V. S. Sreevidya, J. Sudhir, J. V. Savithri, Y. Gowda, C. B. Rao, V. Benegal, P. P. Majumder, A. Anand, S. K. Brahmachari and S. Jain, Association analysis of CAG repeat at the KCNN3 locus in Indian patients with Bipolar Disorder and Schizophrenia, American Journal of Medical Genetics: Neuropsychiatric Genetics 96, 744 - 748 (2000).

  311. K. Sumathy, R. Jayalakshmi, M. S. Shivayogi and H. Balaram, Cloning and characterization of the Plasmodium falciparum adenylosuccinate synthetase gene, Current Science 78, 101 - 105 (2000).

  312. I. N. S. Subbayya, S. Sukumaran, K. Shivashankar and H. Balaram, Unusual substrate specificity of a chimeric hypoxanthine-guanine phosphoribosyltransferase containing segments from the Plasmodium falciparum and human enzymes, Biochemical and Biophysical Research Communications 272, 596 - 602 (2000).

  313. I. N. S. Subbayya and H. Balaram, Evidence of multiple active states of Plasmodium falciparum Hypoxanthine-guanine-xanthine phosphoribosyltransferase, Biochemical and Biophysical Research Communications 279, 433 - 437 (2000).

  314. R. Lakshmi, V. Baskar and U. Ranga, Extraction of Superior Quality Plasmid DNA by a Combination of Modified Alkaline Lysis and Silica Matrix, Analytical Biochemistry 272, 109 - 112 (1999).

  315. P. Gopal, S. S. Ray, R. Ghokale, H. Balaram, M. R. N. Murthy and P. Balaram, Cavity creating mutation at the dimer interface of Plasmodium falciparum triosephosphate isomerase: restoration of stability by disulfide cross-linking of subunits, Biochemistry 38, 478 - 486 (1999).

  316. R. S. Ghokale, S. S. Ray, H. Balaram and P. Balaram, Unfolding of Plasmodium falciparum triosephosphate isomerase in urea and guanidinium chloride. Evidence for a novel disulfide exchange reaction in a covalently cross-linked mutant, Biochemistry 38, 423 - 431 (1999).

  317. H. Balaram and I. N. S. Subbayya, Tinkering with enzymes, Journal of Indian Institute of Science 79, 49 - 60 (1999).

  318. S. S. Ray, H. Balaram and P. Balaram, Unusual stability of a multiply nicked form of Plasmodium falciparum triosephosphate isomerase, Chemistry and Biology 6, 625 - 637 (1999).

  319. S. Verma, C. Woffendin, I. Bahner, U. Ranga, L. Xu, Z.-Y. Yang, S. R. King, D. B. Kohn and G. J. Nabel, Gene transfer into human umbilical cord blood-derived CD34+ cells by particle-mediated gene transfer, Gene Therapy 5, 692 - 699 (1998).

  320. U. Ranga, C. Woffendin, S. Verma, L. Xu, C. H. June, D. K. Bishop and G. J. Nabel, Enhanced T cell engraftment after retroviral delivery of an antiviral gene in HIV-infected individuals, Proceedings of the National Academy of Sciences of the United States of America 95, 1201 - 1206 (1998).

  321. W. L. Stanford, G.Caruana, K. A. Vallis, M. S. Inamdar, M. Hidaka, V. L. Bautch and A. Bernstein, Expression trapping: Identification of novel genes expressed in hematopoetic and endothelial lineages by gene trapping in ES cells, Blood 92, 4622 - 4631 (1998).

  322. K. Sanyal, S. K. Ghosh and P. Sinha, "The MCM16 gene of the yeast Saccharomyces cerevisiae is required for chromosome segregation.", Molecular and General Genetics 260, 242 - 250 (1998).

  323. U. Ranga, Z.-Y. Yang, L. Xu, D. Littman, C. Woffendin and G. J. Nabel, Cell and viral regulatory elements enhance the efficacy of an HIV inhibitory gene, Journal of Virology 71, 7020 - 7029 (1997).

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