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Sebastian C PeterGovindaraju TSubi Jacob GeorgeKanishka Biswas
Sridhar RajaramJayanta Haldar


  1. K. Rajasekhar, K. Mehta and T. Govindaraju, Hybrid Multifunctional Modulators Inhibit Multifaceted Aβ Toxicity and Prevent Mitochondrial Damage, ACS Chem. Neurosci. (2018). In Press.

  2. M. B. Avinash and T. Govindaraju, Architectonics: Design of Molecular Architecture for Functional Applications, Acc. Chem. Res. 51, 414 - 426 (2018).

  3. Y. V. Suseela, Nagarjun Narayanaswamy, Sumon Pratihar and T. Govindaraju, Far-red fluorescent probes for canonical and non- canonical nucleic acid structures: current progress and future implications  , Chem. Soc. Rev. 47, 1098 - 1131 (2018).

  4. C. Madhu, B. Roy, P. Makam and T. Govindaraju, Bicomponent β-sheet assembly of dipeptide-fluorophores of opposite polarity and sensitive detection of nitro-explosives  , Chem. Commun 54, 2280 - 2283 (2018).

  5. M. Pandeeswar, R. Shilpa, A. E. Kandjani, S. R Periasamy, Y. M.Sabri, C. Madhu, S. K. Bhargava, T. Govindaraju, SERS and fluorescence-based ultrasensitive detection of mercury in water, Biosens. Bioelectron. 100, 556 - 564 (2018).

  6. H. Khare, D. Dey, C. Madhu, D. Senapati, S. Raghothama, T. Govindaraju and S. Ramakumar, Conformational heterogeneity in tails of DNA-binding proteins is augmented by proline containing repeats  , Mol. BioSyst. 13, 2531 - 2544 (2017).

  7. S. Manchineella, N. A. Murugan, T. Govindaraju, Cyclic Dipeptide-Based Ambidextrous Supergelators: Minimalistic Rational Design, Structure-Gelation Studies, and In Situ Hydrogelation (Invited Article for a Special Issue), Biomacromolecules 18, 3581 - 3590 (2017).

  8. S. Manchineella, C. Voshavar, T. Govindaraju, Radical‐Scavenging Antioxidant Cyclic Dipeptides and Silk Fibroin Biomaterials (Invited Article for a Special Issue)  , Eur. J. Org. Chem 2017, 4363 - 4369 (2017).

  9. K. Rajasekhar, N. Narayanaswamy, N. A. Murugan, K. Viccaro, H-G. Lee, K. Shah, T. Govindaraju, Aβ plaque-selective NIR fluorescence probe to differentiate Alzheimer's disease from tauopathies, Biosens. Bioelectron. 98, 54 - 61 (2017).

  10. C. Madhu, C. Voshavar, K. Rajasekhar and T. Govindaraju , Cyclic dipeptide-based cell-penetrating peptidomimetics for effective DNA delivery, Org. Biomol. Chem 15, 3170 - 3174 (2017).

  11. K. Rajasekhar, A. J. Achar and T. Govindaraju, A red-NIR emissive probe for the selective detection of albumin in urine samples and live cells  , Org. Biomol. Chem 15, 1584 - 1588 (2017).

  12. S. Manchineella and T. Govindaraju, Molecular self-assembly of cyclic dipeptide derivatives and their applications (Invited article for 5th Anniversary Special Issue), ChemPlusChem (2017). In Press.

  13. M. Pandeeswar, S. P. Senanayak and T. Govindaraju, Nanoarchitectonics of small molecule and DNA for ultrasensitive detection of mercury   , ACS Appl. Mater. Interfaces 8, 30362 - 30371 (2016).

  14. Y. V. Suseela, S. Das, S. K. Pati and T. Govindaraju, Imidazolyl-naphthalenediimide-based threading intercalators of DNA , ChemBioChem 17, 2162 - 2171 (2016).

  15. M. B. Avinash, K. V. Sandeepa, and T. Govindaraju, Emergent behaviors in kinetically controlled dynamic self-assembly of synthetic molecular systems , ACS Omega 1, 378 - 387 (2016).

  16. S. Manchineella, G. Thrivikraman, B. Basu and T. Govindaraju, Surface functionalized silk fibroin films as a platform to guide neuron-like differentiation of human mesenchymal stem cells, ACS Appl. Mater. Interfaces 8, 22849 - 22859 (2016).

  17. K. Rajasekhar, C. Madhu and T. Govindaraju, Natural tripeptide-based inhibitor of multifaceted amyloid β toxicity, ACS Chem. Neurosci. 7, 1300 - 1310 (2016).

  18. M. Pandeeswar, S. P. Senanayak, K. S. Narayan and T. Govindaraju, Multi-stimuli responsive charge-transfer hydrogel for room temperature organic ferroelectric thin-film devices     , J. Am. Chem. Soc. 138, 8259 - 8268 (2016).

  19. N. Narayanaswamy, R. R. Nair, Y. V. Suseela, D. K. Saini and T. Govindaraju, Molecular beacon-based DNA switch for reversible pH sensing in vesicles and live cells       , Chem. Commun. 52, 8741 - 8744 (2016).

  20. K. Rajasekhar, N. Narayanaswamy, N. A. Murugan, G. Kuang, H. Ågren and T. Govindaraju, A high affinity red fluorescence and colorimetric probe for amyloid β aggregates , Sci. Rep 6, 23668 (2016).

  21. M. Pandeeswar and T. Govindaraju, Engineering molecular self-assembly of perylene diimide through pH-responsive chiroptical switching (Invited Article for the first issue)  , Mol. Syst. Des. Eng 1, 202 - 207 (2016).

  22. M. B. Avinash, K. Swathi, K. S. Narayan, and T. Govindaraju, Molecular architectonics of naphthalenediimides for efficient structure-property correlation, ACS Appl. Mater. Interfaces 8, 8678 - 8685 (2016).

  23. S. Manchineella, G. Thrivikraman, K. K. Khanum, P. C. Ramamurthy, B. Basu and T. Govindaraju , Pigmented Silk Nanofibrous Composite for Skeletal Muscle Tissue Engineering (Highlighted in ChemistryViews as Pigments in Tissue Engineering)  , Adv. Healthcare Mater. 05, 1222 - 1232 (2016).

  24. N. Narayanaswamy, S. Narra, R. Nair, D. K. Saini, P. Kondaiah and T. Govindaraju, Stimuli-responsive colorimetric and NIR fluorescence combination probe for selective reporting of cellular hydrogen peroxide, Chem. Sci. 7, 2832 - 2841 (2016).

  25. M. B. Avinash, D. Raut, M. K. Mishra, U. Ramamurty and T. Govindaraju, Bioinspired Reductionistic Peptide Engineering for Exceptional Mechanical Properties, Sci. Rep 5, 16070 (2015).

  26. N. Narayanaswamy, S. Das, P. K. Samanta, K. Banu, G. P. Sharma, N. Mondal, S. K. Dhar, S. K. Pati, and T. Govindaraju, Sequence-Specific Recognition of DNA Minor Groove by an NIR-Fluorescence Switch-On Probe and its potential applications , Nucleic Acids Res. 43, 8651 - 8663 (2015).

  27. K. Rajasekhar, M. Chakrabarti and T. Govindaraju, Function and toxicity of amyloid beta and recent therapeutic interventions targeting amyloid beta in Alzheimer's disease (Invited Feature Article), Chem. Commun 51, 13434 - 13450 (2015).

  28. D. Maity, A. Raj, D. Karthigeyanb, T. K. Kundu and T. Govindaraju, A switch-on near-infrared fluorescence-ready probe for Cu(I): live cell imaging, Supramol. Chem. 27, 589 - 594 (2015).

  29. N. Nagarjun, M. Unnikrishnan, M. Gupta and T. Govindaraju, Fluorescence Reporting of G-Quadruplex Structures and Modulating their DNAzyme Activity Using Polyethylenimine-Pyrene Conjugate , Bioorg. Med. Chem. Lett. 25, 2395 - 2400 (2015).

  30. M. Pandeeswar, H. Khare, S. Ramakumar, and T. Govindaraju, Crystallographic insight-guided nanoarchitectonics and conductivity modulation of n-type organic semiconductor through peptide conjugation, Chem. Commun. 51, 8315 - 8318 (2015).

  31. M. Pandeeswar, T. Govindaraju, Bioinspired Nanoarchitectonics of Naphthalene Diimide to Access 2D Sheets of Tunable Size, Shape, and Optoelectronic Properties (Invited Article: Special Issue on Nanoarchitectonics), J. Inorg. Organomet. Polym. 25, 293 - 300 (2015).

  32. K. Rajasekhar, S. N. Suresh, R. Manjithaya and T. Govindaraju, Rationally Designed Peptidomimetic Modulators of AB Toxicity in Alzheimer’s Disease, Sci. Rep 5, 8139 (2015).

  33. A. K. Dwivedi, M. Pandeeswar, and T. Govindaraju, Assembly Modulation of PDI Derivative as a Supramolecular Fluorescence Switching Probe for Detection of Cationic Surfactant and Metal Ions in Aqueous Media, ACS Appl. Mater. Interfaces 6, 21369 - 21379 (2015).

  34. N. Narayanaswamy, G. Suresh, U. D. Priyakumar and T. Govindaraju, Double zipper helical assembly of deoxyoligonucleotides: mutual templating and chiral imprinting to form hybrid DNA ensembles, Chem. Commun 51, 5493 - 5496 (2015).

  35. M. B. Avinash, and T. Govindaraju, Nanoarchitectonics of biomolecular assemblies for functional applications (Invited Feature Article), Nanoscale 6, 13348 - 13369 (2014).

  36. N. Narayanaswamy, M. Kumar, S. Das, R. Sharma, P. K. Samanta, S. K. Pati, S. K. Dhar, T. K. Kundu and T. Govindaraju, A Thiazole Coumarin (TC) Turn-On Fluorescence Probe for AT-Base Pair Detection and Multipurpose Applications in Different Biological Systems, Sci. Rep 4, 6476 (2014).

  37. M. Pandeeswar, H. Khare, S. Ramakumar, and T. Govindaraju, Biomimetic molecular organization of naphthalene diimide in the solid state: tunable (chiro-) optical, viscoelastic and nanoscale properties, RSC Adv 4, 20154 - 20163 (2014).

  38. D. Maity, A. Raj, P. K. Samanta, D. Karthigeyan, T. K. Kundu, S. K. Pati and T. Govindaraju, A probe for ratiometric near-infrared fluorescence and colorimetric hydrogen sulfide detection and imaging in live cells, RSC Adv 4, 11147 - 11151 (2014).

  39. K. Rajasekhar, N. Narayanaswamy,P. Mishra, S. N. Suresh, R. Manjithaya and T. Govindaraju, Synthesis of hybrid cyclic peptoids and identification of autophagy enhancer (Invited Articlefor “Early Career Series”.), ChemPlusChem 79, 25 - 30 (2014).

  40. M. Shivaprasad, V. Prathyusha, U. D. Priyakumar and T. Govindaraju, Solvent-induced helical assembly and reversible chiroptical switching of chiral cyclic-dipeptide-functionalized naphthalenediimides, Chem. Eur. J. 19, 16615 - 16624 (2013).

  41. Y. V. Suseela, M. Sasikumar, T. Govindaraju, An effective and regioselective bromination of 1,4,5,8-naphthalenetetracarboxylic dianhydride using tribromoisocyanuric acid, Tetrahedron Lett. 54, 6314 - 6318 (2013).

  42. Y. Hisamatsu, S. Banerjee, M. B. Avinash, T. Govindaraju and C. Schmuck, A supramolecular gel from a quadruple zwitterion that responds to both acid and base, Angew. Chem. Int. Ed 52, 12550 - 12554 (2013).

  43. M. Sasikumar, Y. V. Suseela and T. Govindaraju, Dibromohydantoin: a convenient brominating reagent for 1,4,5,8 – naphthalene-tetracarboxylic dianhydride (Cover Page), Asian J. Org. Chem 2, 779 - 785 (2013).

  44. M. B. Avinash, K. V. Sandeepa and T. Govindaraju, Molecular assembly of amino acid interlinked topologically symmetrical pi-complementary donor-acceptor-donor triads, Beilstein J. Org. Chem 9, 1565 - 1571 (2013).

  45. D. Maity, A. Raj, D. Karthigeyan, T. K. Kundu and T. Govindaraju, Reaction-based probes for Co(II) and Cu(I) with dual output modes: fluorescence live cell imaging, RSC Adv 3, 16788 - 16794 (2013).

  46. M. B. Avinash, P. K. Samanta, K. V. Sandeepa, S. K. Pati, and T. Govindaraju, Molecular architectonics of stereochemically constrained pi–complementary functional modules, Eur. J. Org. Chem 2013, 5838 - 5847 (2013).

  47. M. Pandeeswar and T. Govindaraju, Green fluorescent naphthalene diimide: conducting layered hierarchical 2D nanosheets and reversible probe for detection of aromatic solvents, RSC Adv 3, 11459 - 11462 (2013).

  48. D. Maity, B. Sarkar, S. Maiti and T. Govindaraju, A highly selective reaction-based two-photon probe for Cu+ in aqueous media, ChemPlusChem 78, 785 - 788 (2013).

  49. N. Narayanaswamy, M. B. Aviansh and T. Govindaraju, Exploring hydrogen bonding and weak aromatic interactions induced assembly of adenine and thymine functionalised naphthalenediimides, New J. Chem 37, 1302 - 1306 (2013).

  50. M. B. Avinash and T. Govindaraju, Extremely slow dynamics of an abiotic helical assembly: unusual relevance to the secondary structure of proteins, J. Phys. Chem. Lett 4, 583 - 588 (2013).

  51. D. Maity and T. Govindaraju, Turn-on NIR fluorescence and colourimetric cyanine probe for monitoring thiol content in serum and glutathione reductase assisted glutathione redox process (Inside Cover Page), Org. Biomol. Chem 11, 2098 - 2104 (2013).

  52. D. Maitya, D. Karthigeyan, T. K. Kundu and T. Govindaraju, FRET-based rational strategy for ratiometric detection of Cu(II) and live cell imaging, Sens. Actuators B 162, 831 - 837 (2013).

  53. D. Maity, V. Kumar and T. Govindaraju, Reactive Probes for Ratiometric Detection of Co(II) and Cu(I) Based on ESIPT Mechanism , Org. Lett. 14, 6008 - 6011 (2012).

  54. M. B. Avinash, E. Verheggen, C. Schmuck and T. Govindaraju, Self-cleaning Functional Molecular Materials, Angew. Chem., 124, 10470–10474 ( 2012);, Angew. Chem. Int. Ed 51, 10324 - 10328 (2012).

  55. T. Govindaraju and M. B. Avinash, Two-dimensional nanoarchitectonics: organic and hybrid materials (Cover Page), Nanoscale 4, 6102 - 6117 (2012).

  56. M. B. Avinash and T. Govindaraju, Amino Acid Derivatized Arylenediimides: A Versatile Modular Approach for Functional Molecular Materials , Adv. Mater 24, 3905 - 3922 (2012).

  57. T. Govindaraju, Designing biomimetic systems using nature-inspired supramolecular chemistry principles (Invited Review Article), Proc. Indian Natl. Sci. Acad 78, 209 - 232 (2012).

  58. M. Shivaprasad and T. Govindaraju, Hydrogen bond directed self-assembly of cyclic dipeptide derivatives: Gelation and ordered hierarchical architectures , RSC Advances 2, 5539 - 5542 (2012).

  59. M. Pandeeswar, M. B. Avinash and T. Govindaraju, Chiral transcription and retentive helical memory: probing peptide auxiliaries appended naphthalenediimides for their one dimensional molecular organization (Inside Cover page, Article), Chem. Eur. J 18, 4818 - 4822 (2012).

  60. D.Das, Z. Tnimov, U. T.T. Ngyen, D. Abankwa, H. Lo, Y. Wu, T. Govindaraju, R. S. Goody, H. Waldmann and K. Alexandrov, Flexible and General Synthesis of Functionalized Phosphoisoprenoids for the Study of Prenylation In Vivo and In Vitro, ChemBioChem 13, 674 - 683 (2012).

  61. U. Maitra, M. Pandeeswar and T. Govindaraju, Covalent crosslinking of carbon nanostructures (Cover page, article), J. Chem. Sci 124, 551 - 556 (2012).

  62. D. Maity and T. Govindaraju, Differentially selective sensor with fluorescence turn-on response to Zn(II) and dual-mode ratiometric response to Al(III) in aqueous media, Chem. Commun. 48, 1039 - 1041 (2012).

  63. N. Narayanaswamy and T. Govindaraju, Aldazine-basedcolorimetric sensors for Cu(II) and Fe(II), Sens. Actuators B: Chemical 161, 304 - 310 (2012).

  64. T. Govindaraju, Spontaneous self-assembly of aromatic cyclic dipeptide into fibre bundles with high thermal stability and propensity for gelation, Supramol. Chem. 23, 759 - 767 (2011).

  65. D. Maity and T. Govindaraju, Highly selective colorimetric Chemosensor for Co(II), Inorg. Chem. 50, 11282 - 11284 (2011).

  66. D. Maity and T. Govindaraju, Naphthaldehyde–Urea/Thiourea Conjugates as Turn-on Fluorescent Probes for Al(III) Based on Restricted C=N Isomerization, Eur. J. Inorg. Chem 5479 - 5489 (2011).

  67. N. Narayanaswamy, D. Maity and T. Govindaraju, Reversible fluorescence sensing of zinc based on pyridine-constrained bis(triazole-linked hydroxyquinoline) sensor, Supramol. Chem. 5479 - 5485 (2011).

  68. M. Shivaprasad and T. Govindaraju, Rhodamine based bright red colourimetric and turn-on fluorescence chemosensor for selective detection of copper (Invited Article), Mater. Technol. 26, 168 - 172 (2011).

  69. D. Maity, A. K. Manna, D. Karthigeyan, T. K. Kundu, S. K. Pati, and T. Govindaraju, Visible-near infrared and fluorescent copper sensors based on julolidine conjugates: selective detection and fluorescence imaging in living cells. (Frontispiece), Chem. Eur. J. 17, 11152 - 11161 (2011).

  70. M. B. Avinash and T. Govindaraju, Engineering Molecular Organization of Naphthalenediimides: Large Nanosheets with Metallic-Conductivity and Attoliter Containers (Back Cover article), Adv. Funct. Mater 20, 3875 - 3882 (2011).

  71. T. Govindaraju, M. Pandeeswar, K. Jayaramulu, G. Jaipuria and H. S. Atreya, Spontaneous self-assembly of designed cyclic dipeptide (Phg-Phg) into two dimensional nano and mesosheets, Supramol. Chem. 23, 487 - 492 (2011).

  72. M. B. Avinash and T. Govindaraju, A bio-inspired design strategy: Organization of tryptophan-appended naphthalenediimide into well-defined architectures induced by molecular interactions   (Cover Article), Nanoscale 3, 2536 - 2543 (2011).

  73. D. Maity and T. Govindaraju, Highly Selective Visible and Near-IR Sensing of Cu(II) Based on Thiourea–Salicylaldehyde Coordination in Aqueous Media, Chem. Eur. J. 17, 1410 - 1414 (2011).

  74. D. Maity and T. Govindaraju, Conformationally constrained (coumarin-triazolyl-bipyridyl) click fluoroionophore as a selective Al(III) sensor, Inorg. Chem. 49, 7229 - 7231 (2010).

  75. D. Maity and T. Govindaraju, Pyrrolidine constrained bipyridyl-dansyl click fluoroionophore as selective Al(III) sensor, Chem. Commun. 46, 4499 - 4501 (2010).

  76. M. B. Avinash, K. S. Subrahmanyam, Y. Sundarayya and T. Govindaraju, Covalent modification and exfoliation of graphene oxide using ferrocene   (most accessed article)  , Nanoscale 2, 1762 - 1766 (2010).

  77. T. Govindaraju, P. Jonkheijm, L. Gogolin, H. Schroeder, C. F. W. Becker, C. M. Niemeyer and H. Waldmann, Surface immobilization of biomolecules by click sulfonamide reaction, Chem. Commun. 3723 - 3725 (2008).

  78. T. Govindaraju, P. J. Bertrics, R. T. Raines and N. L. Abbott, Using measurements of anchoring energies of liquid crystals on surfaces to quantify proteins captured by immobilized ligands, J. Am. Chem. Soc 129, 11223 - 11231 (2007).

  79. T. Govindaraju, V. Madhuri, V. A. Kumar and K. N. Ganesh, Cyclohexanyl peptide nucleic acids (chPNAs) for Preferential RNA binding: Effective tuning of dihedral angle ? in PNAs for DNA/RNA discrimination, J. Org. Chem. 71, 14 - 21 (2006).

  80. T. Govindaraju, Microwave assisted fast and clean conversion of mesylate to azide: Synthesis of (1S,2R/1R,2S)-1-azido-2-carbocyclic amines, immediate precursor to vicinal-1,2- cis-diamines, Indian J. Chem. B 45B, 1492 - 1498 (2006).

  81. T. Govindaraju and V. A. Kumar, Backbone extended pyrrolidine PNA (bepPNA): a chiral PNA for selective RNA recognition, Tetrahedron 62, 2321 - 2330 (2006).

  82. T. Govindaraju and V. A. Kumar, Backbone extended pyrrolidine peptide nucleic acids (bepPNA): Synthesis, characterization and DNA/RNA binding studies, Chem. Commun 495 - 497 (2005).

  83. T. Govindaraju, V. A. Kumar and K. N. Ganesh, Cyclohexanyl and Cyclopentanyl PNAs: Conformationally preorganized PNAs with steric filters for selective binding of RNA, J. Am. Chem. Soc 127, 4144 - 4145 (2005).

  84. T. Govindaraju, V. A. Kumar and K. N. Ganesh, Synthesis and evaluation of (1S,2R/1R,2S)-aminocyclohexyl-glycyl PNAs as conformationally pre-organized PNA analogues for DNA/RNA recognition, J. Org. Chem 69, 1858 - 1865 (2004).

  85. T. Govindaraju, V. A. Kumar and K. N. Ganesh, cis-Cyclopentyl PNA (cpPNA) as constrained chiral PNA analogues: Stereochemical dependence of DNA/RNA hybridization, Chem. Commun 860 - 861 (2004).

  86. T. Govindaraju, V. A. Kumar and K. N. Ganesh, (1S,2R/1R,2S)-cis-Cyclopentyl PNA (cpPNA) as constrained PNA analogues: Synthesis and evaluation of aeg-cpPNA chimera and stereopreferences in hybridization with DNA/RNA, J. Org. Chem 69, 5725 - 5734 (2004).

  87. T. Govindaraju, R. G. Gonnade, M. M. Bhadbhade, V. A. Kumar and K. N. Ganesh, (1S,2R/1R,2S)-Aminocyclohexyl  Glycyl Thymine PNA: Synthesis, monomer crystal structures, and DNA/RNA hybridization, Org. Lett 5, 3013 - 3016 (2003).

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