Chromatin
remodeling is an important event in the eukaryotic nucleus
rendering nucleosomal DNA accessible for various transaction processes.
The dynamic nature of chromatin is facilitated by Remodeling Factors
through participation of the collective action of (a) ATP
and (b) Non-ATP dependent factors. Considering the importance
of these factors in mammals and eukaryotes, 'CREMOFAC',
a dedicated and frequently updated web-database for chromatin remodeling
factors has been developed.
The
database harbors 64 types of remodeling factors
from 49 different organisms reported in literature
and facilitates a comprehensive search for them. In addition, it
also provides in-depth information for the factors
reported in the three widely studied mammals namely, human,
mouse and rat. Further, information on literature, pathways,
and phylogenetic relationships has also been covered.

The
'Simple and Advanced Search' feature can be used
to search the database through various possible queries to extract
useful data. The 'Download Database' section provides
for convenient downloading of a large number of the chromatin remodeling
protein sequences in various organisms while the 'Phylogeny
Trees' feature highlights the phylogenetic relationship
among various organisms for a given factor.
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