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  • Jiaul Hoque, Brinta Bhattacharjee, Relekar G. Prakash, Krishnamoorthy Paramanandham,and Jayanta Haldar*; “Dual Function Injectable Hydrogel for Controlled Release of Antibiotic and Local Antibacterial Therapy”, Biomacromolecules, 2017, (accepted)

  • Chandrasekhar Challa, Jaice Ravindran, Mohini Mohan Konai, Sunil Varughese, Jubi Jacob, B. S. Dileep Kumar, Jayanta Haldar and Ravi S. Lankalapalli*; “Expedient Synthesis of Indolo[2,3‑b]quinolines, Chromeno[2,3‑b]indoles, and 3‑Alkenyl-oxindoles from 3,3′-Diindolylmethanes and Evaluation of Their Antibiotic Activity against Methicillin-Resistant Staphylococcus aureus”, ACS Omega, 2017, (accepted)

  • Divakara S.S.M. Uppu, Mohini M. Konai, Paramita Sarkar, Sandip Samaddar, Isabel C M Fensterseifer, Celio Farias-Junior, Krishnamoorthy Paramanandam, Bibek R. Shome, Octávio L Francob,and Jayanta Haldar*; “Membrane-Active Macromolecules Kill Antibiotic-Tolerant Bacteria and Potentiate Antibiotics Towards Gram-negative Bacteria”, PLoS One, 2017, (accepted)

  • Mohini Mohan Konai, Utsarga Adhikary and Jayanta Haldar*; “Design and Solution Phase Synthesis of Membrane Targeting Lipopeptides with Selective Antibacterial Activity”, Chem. Eur. J., 2017, (accepted)

  • Chandradhish Ghosh, Paramita Sarkar, Sandip Samaddar, Divakara S.S.M. Uppu and Jayanta Haldar*; “L-lysine based lipidated biphenyls as agents with anti-biofilm andanti-inflammatory properties that also inhibit intracellular bacteria”, Chem. Comm., 2017, 53, 8427-8430

  • Jiaul Hoque and Jayanta Haldar*; “Direct Synthesis of Dextran-based Antibacterial Hydrogels for Extended Release of Biocides and Eradication of Topical Biofilms”, ACS Appl. Mater. Interfaces, 2017, 9, 15975–15985

  • Chandradhish Ghosh, Vikas Yadav, Waleed Younis, Haroon Mohammad,Youssef A. Hegazy, Mohamed N. Seleem, Kaustuv Sanyal, and Jayanta Haldar*; “Aryl-alkyl-lysines: Membrane-active fungicides that act against biofilms of Candida albicans”, ACS Infect. Dis., 2017, 3, 293-301

  • Mohini Mohan Konai and Jayanta Haldar*; “Fatty Acid Comprising Lysine Conjugates: Anti-MRSA Agents that Display In-vivo Efficacy by Disrupting Biofilms with no Resistance Development”, Bioconjugate Chem., 2017, 28, 1194–1204

  • Jiaul Hoque, Relekar G. Prakash, Krishnamoorthy Paramanandham, Bibek R. Shome, and Jayanta Haldar*; “A Biocompatible Injectable Hydrogel with Potent Wound Healing and Antibacterial Properties”, Mol. Pharmaceutics, 2017, 14, 1218–1230

  • Paramita Sarkar, Venkateswarlu Yarlagadda, Chandradhish Ghosha and Jayanta Haldar*; “A review on cell wall synthesis inhibitors with an emphasis on glycopeptide antibiotics”, Med. Chem.Comm., 2017, 8, 516-533 (Invited Review).

  • Chandradhish Ghosh, Shweta Chaubey, Utpal Tatu and Jayanta Haldar*; “Aryl-alkyl-lysines: Small Molecular Membrane-active Antiplasmodial Agents”, Med. Chem.Comm., 2017, 8, 434-439.

  • Stuart D. Dowall*, Kevin Bewley, Robert J. Watson, Seshadri S. Vasan,Chandradhish Ghosh, Mohini M. Konai, Gro Gausdal, James B. Lorens, Jason Long,Wendy Barclay, Isabel Garcia-Dorival, Julian Hiscox, Andrew Bosworth, Irene Taylor,Linda Easterbrook, James Pitman, Sian Summers, Jenny Chan-Pensley, Simon Funnell,Julia Vipond, Sue Charlton, Jayanta Haldar, Roger Hewson and Miles W. Carroll; “Antiviral Screening of Multiple Compounds against Ebola Virus”, Viruses, 2016, 8, E277.

  • Jiaul Hoque, Mohini M. Konai, Shanola S. Sequeira, Sandip Samaddar and Jayanta Haldar*; “Antibacterial and Antibiofilm Activity of Cationic Small Molecules with Spatial Positioning of Hydrophobicity: An in Vitro and in Vivo Evaluation”, J. Med. Chem., 2016, 59, 10750–10762.

  • Jiaul Hoque, Padma Akkapeddi, Divakara S. S. M. Uppu and Jayanta Haldar*; “A Biodegradable Polycationic Paint that Kills Bacteria In Vitro and In Vivo”, ACS Appl. Mater. Interfaces, 2016, 8, 29298–29309.

  • Jiaul Hoque, Utsarga Adhikary, Vikas Yadav, Sandip Samaddar, Mohini M. Konai, Relekar G. Prakash, Krishnamoorthy Paramanandham, Bibek R. Shome, Kaustuv Sanyal and Jayanta Haldar*; “Chitosan Derivatives Active against Multi-Drug-Resistant Bacteria and Pathogenic Fungi: In Vivo Evaluation as Topical Antimicrobials”, Mol. Pharmaceutics, 2016, 13, 3578–3589.

  • Chandradhish Ghosh, Mohini M. Konai, Paramita Sarkar, Sandip Samaddar and Jayanta Haldar*; “Designing simplest lipopeptoidssimple lipidated lysines: Bifurcation imparts selective antibacterial activity”, ChemMedChem, 2016, 11, 2376-2371.

  • Divakara S. S. M. Uppu, Sandip Samaddar, Jiaul Hoque, Mohini M. Konai, Krishnamoorthy Paramanandham, Bibek R. Shome and Jayanta Haldar*; “Side Chain Degradable Cationic-amphiphilic Polymers with Tunable Hydrophobicity Show In-vivo Activity”, Biomacromolecules, 2016, 17,3094-3102.

  • Divakara S. S. M. Uppu, Mohini M. Konai, Upayan Baul, Priyank Singh, Tjalling K. Siersma, Sandip Samaddar, Satyavani Vemparala, Leendert W. Hamoen, Chandrabhas Narayana and Jayanta Haldar*; “Isosteric substitution in Cationic-amphiphilic polymers Reveals an Important Role for Hydrogen Bonding in Bacterial Membrane Interactions.”, Chem. Sci., 2016, 7, 4613-4623

  • Venkateswarlu Yarlagadda, Paramita Sarkar, Sandip Samaddar and Jayanta Haldar*; “Incorporation of Pyrophosphate Binding Ability to Vancomycin: A Strategy to Combat Vancomycin-resistant Bacteria ”, Angew. Chem. Int. Ed., 2016, 27, 7836-7840. "Very important paper in antibiotics"

  • Divakara S. S. M. Uppu, Mithun Bhowmick, Sandip Samaddar and Jayanta Haldar*; “Cyclization and Unsaturation rather than Isomerisation of Side Chains govern the Selective Antibacterial Activity of Cationic-amphiphilic polymers ”, Chem. Comm., 2016, 52, 4644-4647.

  • Divakara S. S. M. Uppu and Jayanta Haldar*; “Lipopolysaccharide Neutralization by Cationic-amphiphilic Polymers through Pseudo-aggregate Formation ”, Biomacromolecules, 2016, 17(3), 862–873

  • Venkateswarlu Yarlagadda, Sandip Samaddar and Jayanta Haldar*; “Intracellular Activity of a Membrane-active Glycopeptide Antibiotic Against Methicillin-resistant Staphylococcus aureus Infection.”, J. Glob. Antimicrob. Resist., 2016, 5, 71-74.

  • Divakara S. S. M. Uppu, Sandip Samaddar, Chandradhish Ghosh, Krishnamoorthy Paramanandam, Bibek R. Shome, and Jayanta Haldar*; “Amide Side Chain Amphiphilic Polymers Disrupt Surface Established Bacterial Bio-films and Protect Mice from Chronic Acinetobacter baumannii Infection”, Biomaterials, 2016, 74, 131-143.

  • Chandradhish Ghosh, Goutham B. Manjunath, Mohini M. Konai, Divakara S. S. M. Uppu, Jiaul Hoque, Krishnamoorthy Paramanandham, Bibek R. Shome and Jayanta Haldar*; “Aryl-Alkyl-Lysines: Agents That Kill Planktonic Cells, Persister Cells, Biofilms of MRSA and Protect Mice from Skin-infection”, PLoS One, 2015, 10, e0144094.

  • Chandradhish Ghosh, Goutham B. Manjunath, Mohini M. Konai, Divakara S. S. M. Uppu, Krishnamoorthy Paramanandham, Bibek R. Shome, Raju Ravikumar and Jayanta Haldar*; “Aryl-alkyl-lysines: Membrane-Active Small Molecules Active against Murine Model of Burn Infection”, ACS Infect. Dis., 2016, 2, 111–122.

  • Venkateswarlu Yarlagadda, Goutham B. Manjunath, Paramita Sarkar, Padma Akkapeddi, Krishnamoorthy Paramanandham, Bibek R. Shome, Raju Ravikumar and Jayanta Haldar*; “Glycopeptide Antibiotic to Overcome The Intrinsic Resistance of Gram-negative Bacteria.”, ACS Infect. Dis., 2015, 1, 469–478.

  • Venkateswarlu Yarlagadda, Paramita Sarkar, Goutham B. Manjunath and Jayanta Haldar*; “Lipophilic Vancomycin Aglycon Dimer with High Activity against Vancomycin-resistant Bacteria.”, Biorg. Med. Chem. Lett., 2015, 25(23), 5477-5580.

  • Mohini M. Konai, Utsarga Adhikary, Sandip Samaddar, Chandradhish Ghosh and Jayanta Haldar*; “Structure-activity Relationship of Amino acid Tunable Lipidated Norspermidine Conjugates: Disrupting Biofilms with Potent Activity against Bacterial Persisters.”, Bioconjug. Chem., 2015, 26, 2442-2453.

  • Venkateswarlu Yarlagadda, Sandip Samaddar, Krishnamoorthy Paramanandam, Bibek R. Shome, and Jayanta Haldar*; “Membrane Disruption and Enhanced Inhibition of Cell wall Biosynthesis: A Synergistic Approach to Tackle Vancomycin-resistant Bacteria”, Angew. Chem., Int. Ed., 2015, 54, 13644-13649. "Hot paper in drug design"

  • Mohini M. konai and Jayanta Haldar*; “Lysine-based Small Molecules That Disrupt Biofilms and Kill Both Actively Growing Planktonic and Non-dividing Stationary Phase Bacteria”, ACS Infectious Diseases, 2015, 1, 469–478.

  • Jiaul Hoque, Mohini M. Konai, Sandip Samaddar, Spandhana Gonuguntla, Goutham B Manjunath, Chandradhish Ghosh and Jayanta Haldar*; “Selective and Broad Spectrum Amphiphilic Small Molecules to Combat Bacterial Resistance and Eradicate Biofilm”, Chem. Comm., 2015, 51, 13670-13673.

  • Chandradhish Ghosh and Jayanta Haldar*; “Membrane Active Small Molecules: Designs Inspired from Antimicrobial Peptides”, ChemMedChem., 2015, 10(10), 1606-1624

  • Jiaul Hoque, Mohini M. Konai, Spandhana Gonuguntla, Goutham B. Manjunath, Sandip Samaddar, Venkateswarlu Yarlagadda and Jayanta Haldar*; “Membrane Active Small Molecules Show Selective Broad Spectrum Antibacterial Activity with No Detectable Resistance and Eradicate Biofilms”, J. Med. Chem., 2015, 58, 5486-5500.

  • Venkateswarlu Yarlagadda, Mohini M. Konai, Krishnamoorthy Paramanandam, Venugopal C. Nimita, Bibek R. Shome, and Jayanta Haldar*; “In-vivo Efficacy and Pharmacological Properties of A Novel Glycopeptide (YV4465) against Vancomycin-Intermediate Staphylococcus aureus (VISA)”, Int. J. Antimicrob. Agents, 2015, 46, 446-450.

  • Venkateswarlu Yarlagadda, Mohini M. Konai, Goutham B. Manjunath, Relekar G. Prakash, Bhuvana Mani, Krishnamoorthy Paramanandham, Shome B. Ranjan, Raju Ravikumar, Subhankari P. Chakraborty, Somenath Roy and Jayanta Haldar*; “In-vivo Antibacterial Activity and Pharmacological Properties of Membrane Active Glycopeptide Antibiotic (YV11455)”, Int. J. Antimicrob. Agents, 2015, 45(6), 627-634

  • Divakara S. S. M. Uppu, Chandradhish Ghosh and Jayanta Haldar*; “Surviving Sepsis in The Era of Antibiotic Resistance: Are There Any Alternative Approaches to Antibiotic Therapy?”, Microb. Pathog., 2015, 80C, 7-13.

  • Divakara S. S. M. Uppu, Goutham B. Manjunath, Venkateswarlu Yarlagadda, Jyothi E. Kaviyil, Raju Ravikumar, Krishnamoorthy Paramanandham, Bibek R. Shome and Jayanta Haldar*; “Membrane-active Macromolecules Resensitize NDM-1 Gram-negative Clinical Isolates to Tetracycline Antibiotics”, PLoS One, 2015, 10, e0119422.

  • Jiaul Hoque, Padma Akkapeddi, Vikas Yadav, Goutham B. Manjunath, Divakara S. S. M. Uppu, Mohini M. Konai,Venkateswarlu Yarlagadda, Kaustuv Sanyal and Jayanta Haldar*; “Broad Spectrum Antibacterial and Antifungal Polymeric Paint Materials: Synthesis, Structure-activity Relationship and Membrane-active Mode of Action”, ACS Appl. Mater. Interfaces, 2015, 7(3), 1804-1815

  • Divakara S. S. M. Uppu, Chandradhish Ghosh and Jayanta Haldar*; “Alternative Strategies to Target Quorum Sensing (QS): Combination of QS Inhibitors with Antibiotics and Nanotechnological Approaches”, A Chapter in a book entitled "Quorum Sensing vs Quorum Quenching: A battle with no end in sight", Springer, 2015, 335-342.

  • Venkateswarlu Yarlagadda, Mohini M. Konai, Goutham B. Manjunath, Chandradhish Ghosh and Jayanta Haldar*; “Tackling Vancomycin-resistant Bacteria with Lipophilic-vancomycin-carbohydrate Conjugates”, J. Antibiot., 2015, 68, 302-312.

  • Mohini M. Konai, Chandradhish Ghosh, Venkateswarlu Yarlagadda, Sandip Samaddar and Jayanta Haldar*; “Membrane Active Phenylalanine Conjugated Lipophilic Norspermidine Derivatives with Selective Antibacterial Activity.”, J. Med. Chem., 2014, 57, 9409–9423.

  • Divakara S. S. M. Uppu, Jiaul Hoque and Jayanta Haldar*; “Engineered Polymers and Organic-inorganic Hybrids as Antimicrobial Materials for Water Disinfection”, A Chapter in a book entitled "Aquananotechnology: Global Prospects", CRC Press-Taylor and Francis Group, 2014, Chapter 12, 218-238.

  • Venkateswarlu Yarlagadda, Padma Akkapeddi, Goutham B. Manjunath and Jayanta Haldar*; “Membrane Active Vancomycin Analogues: A Strategy to Combat Bacterial Resistance”, J. Med. Chem, 2014, 57, 4558–4568.

  • J. Hoque, S.Gonuguntla, Venkateswarlu Yarlagadda, Vinod K. Aswal and Jayanta Haldar*; “Effect of Amide Bonds on the Self-assembly of Gemini Surfactants ”, Phys. Chem. Chem. Phys., 2014, 16, 11279-11288.

  • Chandradhish Ghosh, Goutham B. Manjunath, Padma Akkapeddi, Venkateswarlu Yarlagadda, Jiaul Hoque, Divakara S. S. M. Uppu, Mohini M. Konai and Jayanta Haldar*; “Small Molecular Antibacterial Peptoid Mimics: The Simpler The Better!”, J. Med. Chem, 2014, 57, 1428–1436.

  • Divakara S. S. M. Uppu, Padma Akkapeddi, Goutham B. Manjunath, Venkateswarlu Yarlagadda, Jiaul Hoque and Jayanta Haldar*; “Polymers with Tunable Side-chain Amphiphilicity as Non-hemolytic Antibacterial Agents”, Chem. Commun., 2013, 49, 9389-9391.

  • Chia Min Lee, Alisha K. Weight, Jayanta Haldar, Ling Wang, Alexander M. Klibanov and Jianzhu Chen; “Polymer-attached Zanamivir Inhibits Synergistically Both Early and Late Stages of Influenza Virus Infection”, Proc. Natl. Acad. Sci. USA 2012, 109, 20385-20390.

  • Jiaul Hoque, Padma Akkapeddi, Venkateswarlu Yarlagadda, Divakara S. S. M. Uppu, Pratik Kumar and Jayanta Haldar*; “Cleavable Cationic Antibacterial Amphiphiles: Synthesis, Mechanism of Action, and Cytotoxicities”, Langmuir, 2012, 28, 12225-122234.

  • Jiaul Hoque, Pratik Kumar, Vinod K. Aswal and Jayanta Haldar*; “Aggregation Properties of Amide Bearing Cleavable Gemini Surfactants by Small Angle Neutron Scattering and Conductivity Studies”, J. Phys. Chem. B, 2012, 116, 9718-9726.

  • Alisha K. Weight, Jayanta Haldar, Luis Alvarez De Cienfuegos, Larisa V Gubareva, Terrence M Tumpey, Jianzhu Chen and Alexander M. Klibanov,  “Attaching Zanamivir to A Polymer Markedly Enhances Its Activity against Drug-resistant Strains of Influenza A Viruse”, J. Pharm. Sci. 2011, 100, 831-835.

  • Alyssa M Larson, Bryan Hsu, Debabrata Rautaray, Jayanta Haldar, Jianzhu Chen, and Alexander M. Klibanov; “Hydrophobic Polycationic Coatings Disinfect Poliovirus and Rotavirus Solutions”, Biotechnol. Bioeng. 2011, 108, 720-723. 

  • Jayanta Haldar, Luis Alvarez De Cienfuegos, Terrence M Tumpey, Larisa V Gubareva, Jianzhu Chen and Alexander M. Klibanov; “Bifunctional Polymeric Inhibitors of Influenza A Viruses”; Pharm. Res.  2010, 27, 259-263.

  • Jayanta Haldar, Jianzhu Chen, Terrence M Tumpey, Larisa V Gubareva and Alexander M. Klibanov; “Hydrophobic Polycationic Coatings Inactivate Wild-type and Zanamivir- and/or Oselatamivir-resistant Human and Avian Influenza Viruses”, Biotech. Lett. 2008, 30, 475-479.

  • Jayanta Haldar, Alisha K. Weight and Alexander M. Klibanov“Preparation, Application and Testing of Permanently Antibacterial and Antiviral Coatings”, Nature Protoco., 2007, 2, 2412-2417.

  • Jayanta Haldar, Deqiang An, Luis Alvarez De Cienfuegos, Jianzhu Chen and Alexander M. Klibanov;“Polymer Coatings That Inactivate Both Influenza Virus and Pathogenic Bacteria”, Proc. Natl. Acad. Sci. USA 2006, 103, 17667-17671.

  • Jayanta Haldar, Vinod K. Aswal, Prem S.Goyal and Santanu Bhattacharya.“Unusual Micellar Properties of Multi-headed Cationic Surfactants in Presence of Strong Charge Neutralizing Salts”, J. Colloid Int. Sci. 2005, 282, 156-161.

  • Jayanta Haldar, Paturu Kondiah and Santanu Bhattacharya.“Synthesis and Antibacterial Properties of Novel Hydrolyzable Cationic Amphiphiles. Incorporation of Multiple Headgroups Leads to Impressive Antibacterial Activity” J. Med. Chem. 2005, 48, 3823-3831.

  • Santanu Bhattacharya and Jayanta Haldar.“Microcalorimetric and Conductivity Studies with Micelles Prepared from Multi-headed Pyridinium Surfactants”, Langmuir, 2005, 22, 5747-5751.

  • Jayanta Haldar, Vinod K. Aswal, Prem S.Goyal, and Santanu Bhattacharya. “Aggregation Properties of Novel Cationic Surfactants with Multiple Pyridinium Headgroups. Small-angle Neutron Scattering and Conductivity Studies”, J. Phys. Chem. B, 2004, 108, 11406-11411.

  • Santanu Bhattacharya and Jayanta Haldar.“Thermodynamics of Micellization of Multiheaded Single-chain Cationic Surfactants”, Langmuir, 2004, 20, 7940-7947.

  • Jayanta Haldar, Vinod K. Aswal, Prem S.Goyal, and Santanu Bhattacharya. “Small-angle Neutron Scattering Study of Aggregate Structures of Multi-headed Pyridinium Surfactants in Aqueous Solution”, Pramana, 2004, 63, 303-307.

  • Vinod K. Aswal, Jayanta Haldar, Soma De, Prem S.Goyal, and Santanu Bhattacharya;“Characterization of Vesicles from Ion-paired Gemini Surfactants by Small Angle Neutron Scattering”, Phys. Chem. Chem, Phys., 2003, 5, 907-910.

  • Jayanta Haldar and Santanu Bhattacharya;“The Molecular Design of Surfactant Based Materials”, A Chapter in a book entitled Materials research: current research future projections Eds. R. Chidambaram and S. Banerjee, Allied publishers-New Delhi, 2003, p. 78.

  • Vinod K. Aswal, Jayanta Haldar, Prem S.Goyal and Santanu Bhattacharya;“SANS study of Micellar Aggregation of Multi-headed Surfactants”, Appl. Phys A: Mater. Sci. Proc., 2002, 74, S352-S354.

  • Santanu Bhattacharya and Jayanta Haldar. “Molecular Design of Surfactants to Tailor Its Aggregation Properties”, Colloids Surf. A: Physiochem. Eng. Aspects,  2002, 205, 119-126.

  • Jayanta Haldar, Vinod K. Aswal, Prem S. Goyal and Santanu Bhattacharya; “Role of Incorporation of Multiple Headgroups in Cationic Surfactants on Micellar Properties. Small Angle Neutron Scattering and Fluorescence Studies”, J. Phys. Chem. B, 2001, 105, 12803-12808.

  • Jayanta Haldar, Vinod K. Aswal, Prem S. Goyal and Santanu Bhattacharya. “Molecular Modulation of Surfactant Aggregation in Water. Effect of Incorporation of Multiple Headgroups on Micellar Properties”, Angew. Chem. Int. Ed. 2001, 40, 1228-1232.


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