Commercialized Products Based on Prof.
Kundu’s Innovation
Title of the Invention: Modulators (Inhibitors/Activators) of Histone
Acetyltransferases:
Product:His group has found the first natural inhibitor of
histone acetyltransferase (HAT), anacardic acid, from Cashewnut shell
liquid. Using anacardic acid as synthon, thier group has synthesized the
only known small molecule activator of HAT, specific to p300. These small
molecule compounds have been commercialized for academic research purposes
EMD Biosciences Inc., USA: Product: Anacardic acid
(HAT inhibitor), CTPB (specific activator of HAT, p300)
Alexis, USA. Product: Anacardic acid (HAT
inhibitor) CTPB (specific activator of HAT, p300)
Title of the Invention: Monoclonal Antibodies against NPM1 and Acetylated
NPM1, and Process Thereof
They have identified the sites of acetylation and generated acetylation site
specific antibodies against the modified protein. These antibodies are
highly valuable reagents to elucidate the physiological role of this
chaperone and also could be useful for diagnostic purposes. Very recently,
we have commercialized a set of these antibodies to Merck Millipore and
Abcam. Several other companies have also shown interest to avail the license
for these antibodies.
EMD Biosciences Inc., USA: Product: Anacardic acid (HAT inhibitor), CTPB
(specific activator of HAT, p300)
Alexis, USA. Product: Anacardic acid (HAT inhibitor) CTPB (specific activator
of HAT, p300)
Title of the Invention: Inhibition of Histone Acetyltransferases by CTK7A
and methods thereof.
Product:This is a HAT inhibitor, which inhibits p300
autoacetylation in mice tumor.
EMD Biosciences Inc., USA: Product: Anacardic acid (HAT inhibitor), CTPB
(specific activator of HAT, p300)
Alexis, USA. Product: Anacardic acid (HAT inhibitor) CTPB (specific activator
of HAT, p300)
