Alumni

Connecting the paralogs: contribution of EFHC1 and EFHC2 in juvenile myoclonic epilepsy

Functional characterization of a subtype specific NF-kB motif in HIV-1C viral promoter and its association with the proximal and subtype specific Sp1 site

Studies on molecular genetic aspects of idiopathic generalized epilepsies

“Regulation of Expression and Function of Protein Arginine Methyltransferase 4 (PRMT4/CARM1): Implication in differentiation and Disease”

Current Profile          Publications

”The Role of Aurora Kinases at the Crossroads of Cancer and Differentiation”

Current Profile            Publications

“Functional Mechanisms of Human Transcriptional Coactivator PC4, a Bona Fide Nonhistone Component of chromatin”

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“Post Translational Modifications Regulate Multifunctional Nucleolar Protein NPM1: Implications in oral cancer Manifestation”

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“Functional Cooperativity of Tumor suppressor p53 and Transcriptional coativator PC4:Transcription to repair”

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“Molecular Mechanisms of Inhibition of Histone Acetyltransferases: Implications in Antineoplastic Therapy”

Publications

"Understanding the Role of Post-translational Modifications of Human Non-histone

Chromatin Protein PC4 ''

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“Chromatin modifications by CARM1/PRMT4 and p300/KAT3B in the regulation of gene expression, probed by specific small molecule inhibitors”

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“Modulation of Human Histone Chaperone Nucleophosmin (NPM1) Functions by its Interacting Partners: Implications in Chromatin Dynamics and Transcription”

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“Regulation of p53 Function by Nonhistone Chromosomal Protiens HMGB-1 and PC4”

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"Mechanism Insights into the Substrate-Mediated Regulation of p300 Autoacetylation: Implications in Tumor Suppressor/Oncogene Function"

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“Role of Nucleoplasmin Family of Histone Chaperones, NPM1 and NPM2, in the regulation of Transcription”

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“Chromatin associated protein, PC4 in genome organization and breast cancer manifestation”

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“Regulation of Acetylation- Dependent Chromatin transcription by Human Nucleophosmin, a Histone Chaperone”

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“Role of Non-histone Chromatin Protein PC4 in regulation of Autophagy and Tumorigenesis”

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“Chromatin Organisation in Differentiation and Development: Role of chromatin-associated protein, PC4 and histone modifications”

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“Aurora Kinases Beyond Centrosomes: Role of Transcription Factor's Phosphorylation in Gene Expression and Cell Cycle.”

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“Understanding the mechanisms and gene targets of histone chaperone NPM1 mediated transcriptional regulation”

Current Profile          Publications

Studies on molecular genetic aspects of nonsyndromic hereditary hearing loss

Identification of genetic loci and mutations in SLC1A1 for a sensory epilepsy triggered by touch and temperature stimuli

Molecular genetic aspects of non-syndromic hearing loss in India

Role of NF-kB binding sites in the viral enhancer of HIV-1C promoter in shaping the viral replicative fitness

Funcitonal Significance of HIV-1 Tat signature amino acid residues(SAR)

Safety, efficacy and immunological evaluation of a polyherbal formulation against HIV-AIDS in an open-label clinical trial

Prospective causal genes for genetic generalized epilepsy

On genetic aspects of non-syndromic hearing loss

Evaluation of the efficacy of needle-free intradermal immunization of DNA vectors and recombinant proteins: Implications for optimization of the needle-free technology

Identification of genetic loci for human epilepsies

On genetic aspects of hot water epilepsy, a sensory epilepsy triggered by touch and temperature stimuli

Elucidation of HIV-1 subtype C genetic diversity in Gag and Tat from the clinical cohorts of India: the PTAP motif duplication in p6 Gag confers replication fitness on subtype C

Synergy between enhanced transcriptional strength of the viral promoter and the Tat - autoregulatory circuit accelerates latency establishment in HIV-1C