Alumni

Connecting the paralogs: contribution of EFHC1 and EFHC2 in juvenile myoclonic epilepsy

Currently, Postdoctoral Fellow, CHU Sainte-Justine Research Centre, University of Montreal, QC, Canada

"Elucidating the Functional Implications of Histone Acylation in Adipogenesis and hepatic Steatosis"

Current Profile         Publications

Functional characterization of a subtype specific NF-kB motif in HIV-1C viral promoter and its association with the proximal and subtype specific Sp1 site

Understanding the roles of fumarate in plasmodium metabolism and succinimide in MjGATase stabilization

Studies on molecular genetic aspects of non syndromic hereditary hearing loss

Currently, working at Citadel Precision Medicine LLC, Iselin, New Jersey 08830

Unique molecular properties of HIV-1C reverse transcriptase conferring a possible replication advantage.

Studies on molecular genetic aspects of idiopathic generalized epilepsies

Currently, Assistant Professor, McGovern Medical School, University of Texas Health Science Center at Houston; 7000 Fannin St, Suite 150, Houston, TX 77030 USA

Structure-function studies on three members of the haloacid dehalogenase (HAD) superfamily of enzymes

Currently, Associate Principal Scientist, Mechanistic and Structural Biology, AstraZeneca, Cambridge, England

Chromatin Organisation Mediated Gene Regulatory Function of mrhl lncRNA at the Sox8 locus

Currently at JNCASR, Bengaluru

Functional Mechanisms of Human Transcriptional Coactivator PC4, a Bona Fide Nonhistone Component of chromatin

Studies on LncRNA Mrhl in Mouse Embryonic Stem Cells and Neuronal Lineage Development

Currently working at Centre for Genomics and Child Health Queen Mary University of London, U.K

“Regulation of Expression and Function of Protein Arginine Methyltransferase 4 (PRMT4/CARM1): Implication in differentiation and Disease”

Current Profile          Publications

”The Role of Aurora Kinases at the Crossroads of Cancer and Differentiation”

Current Profile            Publications

“Post Translational Modifications Regulate Multifunctional Nucleolar Protein NPM1: Implications in oral cancer Manifestation”

Current Profile        Publications

"Understanding the Role of Post-translational Modifications of Human Non-histone Chromatin Protein PC4 ''

Current Profile               Publications

“Chromatin modifications by CARM1/PRMT4 and p300/KAT3B in the regulation of gene expression, probed by specific small molecule inhibitors”

Current Profile           Publications

“Modulation of Human Histone Chaperone Nucleophosmin (NPM1) Functions by its Interacting Partners: Implications in Chromatin Dynamics and Transcription”

Current Profile           Publications

"Mechanism Insights into the Substrate-Mediated Regulation of p300 Autoacetylation: Implications in Tumor Suppressor/Oncogene Function"

Current Profile           Publications

“Role of Nucleoplasmin Family of Histone Chaperones, NPM1 and NPM2, in the regulation of Transcription”

Current Profile                     Publications

“Chromatin associated protein, PC4 in genome organization and breast cancer manifestation”

Current Profile           Publications

“Role of Non-histone Chromatin Protein PC4 in regulation of Autophagy and Tumorigenesis”

Current Profile          Publications

“Chromatin Organisation in Differentiation and Development: Role of chromatin-associated protein, PC4 and histone modifications”

Current Profile             Publications

“Aurora Kinases Beyond Centrosomes: Role of Transcription Factor's Phosphorylation in Gene Expression and Cell Cycle.”

Current Profile           Publications

“Understanding the mechanisms and gene targets of histone chaperone NPM1 mediated transcriptional regulation”

Current Profile          Publications

Characterization of Plasmodium falciparum Centromeric  Proteins: CENH3 and CENP-C

Currently, Public Health Scientist, Maryland Department of Health, Laboratories Administration, 1770 Ashland Avenue, Baltimore, Maryland 21205, USA

Characterization and Functional Analysis of a Novel Non-Coding RNA (mrhl) from Mouse

Currently, Vice President at Envisagenics, U.S.A

Studies towards Understanding the Biological Roles of TH2BS11ph Histone Mark and H1t Linker Histone Variant in Mammalian Spermatogenesis

Currently, Scientific Manager at Excelra, Hyderabad,Telengana.

Kinetic Mechanism, Ammonia Channeling and Domain Cross-talk in Plasmodium falciparum GMP Synthetase: an Amidotransferase

Currently, Ramalingaswam Fellow, Centre for Interdisciplinary Research & Innovations, University Of Kashmir

Structure-function studies on successive purine salvage pathway enzymes- hypoxanthine guanine phosphoribosyltransferase and adenylosuccinate synthetase

Currently, Scientific Review Officer at Centers for Disease Control and Prevention, Atlanta

Identification of genetic loci and mutations in SLC1A1 for sensory epilepsy triggered by touch and temperature stimuli

Currently, Research Associate @ Weill Cornell Medicine, Ronald G Crystal Lab, Genetic Medicine, WCMC, 1300 York Avenue, New York, NY, 10065

Functional Cooperativity of Tumor suppressor p53 and Transcriptional coativator PC4:Transcription to repair

Biochemical and Physiological Investigations on Adenosine Monophosphate Deaminase and Haloacid Dehalogenase Superfamily Members from Plasmodium spp

Currently, Post-doctoral Research Associate, the University of Kent, UK 

Biochemical and Molecular Insights into β-ketoacyl-Acyl Carrier Protein reductase (FabG) from Plasmodium falciparum

Currently,  Principal Scientist, IISER Pune, Maharashtra, India

Engineering and evaluation of molecular adjuvants for DNA immunogens based on the HIV transactivator (Tat) proteins from Indian isolates

Towards understanding the role of HILS1 in chromatin remodeling during spermiogenesis

Currently, Senior Research Scientist, Department of Cell Biology,  Albert Einstein College of Medicine, New York, U.S.A 

Biochemical studies on inosine 5'-monophosphate dehydrogenase from the mesophilic protozoan plasmodium falciparum and hyperthermophilic archaeon methanocaldococcus jannaschii

Currently, Scientific Manager, Aragen Life Sciences, Hyderabad

Molecular genetic aspects of non-syndromic hearing loss in India

Currently, Assistant Professor with a joint appointment in the Departments of Pathology and Urology, and is a member of the Harold C. Simmons Comprehensive Cancer Center, UT Southwestern Medical Center, Dallas

Role of NF-kB binding sites in the viral enhancer of HIV-1C promoter in shaping the viral replicative fitness

Funcitonal Significance of HIV-1 Tat signature amino acid residues(SAR)

Safety, efficacy and immunological evaluation of a polyherbal formulation against HIV-AIDS in an open-label clinical trial

Prospective causal genes for genetic generalized epilepsy

Currently, Scientist II, Clevergene, Bangalore

Molecular Mechanisms of Inhibition of Histone Acetyltransferase: Implications in Antineoplastic Therapy

Studies on Plasmodium falciparum Enoyl-ACP Reductase (Fabl)

Currently, Principal Scientist, IIIM, Srinagar, Kashmir, India

"Elucidating the Relevance of Eukaryotic Acetyltransferases in Early Development and Cellular Homeostasis''

Current Profile        Publications

Insights into Post-Translational Modifications of  Transition Proteins, TP1 and TP2 during Mammalian  Spermiogenesis

Currently, Principal Scientist, Cancer Research U.K Cambridge, U.K

On genetic aspects of non-syndromic hearing loss

Currently, Guest lecturer, Centre for Human Genetics, Biotech Park, E-city, Phase-1, Bangalore

Evaluation of the efficacy of needle-free intradermal immunization of DNA vectors and recombinant proteins: Implications for optimization of the needle-free technology

Chromatin Remodeling during Spermiogenesis: Molecular Components involved in Nuclear Import of Transition Protein 2 (TP2) and Role of Acetylation in Modulating TP2 Function 

Currently, Senior Lecturer, Centre for Genomics and Child Health Queen Mary university of London, U.K

Isolation and biological characterization of infectious molecular clones of HIV-1 subtype-C with expanded coreceptor usage from an Indian demented subject

Protein Structure and Dynamics: Studies on the Plasmodial Proteins-Triosephosphate Isomerase (TIM), Hypoxanthine Guanine Phosphoribosyltransferase (HGPRT) and Plasmepsin II

Identification of genetic loci for human epilepsies

Currently, Assistant Professor Ophthalmology-Departmental
Baylor College of Medicine
Houston, TX US

Currently, PhD student, TIFR, Mumbai

Methanocaldococcus jannaschii GMP Synthetase:  Investigations on Aspects of Catalysis and the Role of an Unusual Post-Translational Modification in Structure and Function

Currently, Post-doctoral Fellow, NCBS, Bangalore

Mechanistic underpinnings of substrate recognition, catalysis and allostery in GMP synthetases

Currently, Post-doctoral Fellow, The Francis Crick Institute, UK

On genetic aspects of hot water epilepsy, a sensory epilepsy triggered by touch and temperature stimuli

Currently, Senior Project Associate at Institute of Genomics and Integrative Biology, New Delhi

Elucidation of HIV-1 subtype C genetic diversity in Gag and Tat from the clinical cohorts of India: the PTAP motif duplication in p6 Gag confers replication fitness on subtype C

Assembly Dynamics and structure-function Analysis of an unusual Kinetochore in the Pathogenic Basidiomycetous Budding Yeast Cryptococcus neoformans

Mrhl long non-coding RNA regulates Wnt mediated Sox8 gene expression during spermatogenesis through promoter interaction

Currently working at Laboratory of Epigenetic Regulation Institute of Molecular Genetics Czech Academy of Science, Prague

On molecular genetic analysis of juvenile myoclonic epilepsy

Structural and functional characterization of adenylosuccinate synthetase from a mesophilic parasitic protozoan, plasmodium falciparum and thermophilic archaea, methanocaldococcus jannaschii

Currently, Project Manager at DBT-BIRAC, New Delhi 

“Regulation of p53 Function by Nonhistone Chromosomal Protiens HMGB-1 and PC4”

Understanding Conformational Dynamics and Kinetic Behavior in Plasmodium falciparum  Hypoxanthine
Guanine Xanthine  Phosphoribosyltransferase

Currently, Research Scientist ,University of Nebraska-Lincoln, Lincoln, Nebraska, USA

Understanding the kinetic and structural features of Plasmodium falciparum Sir2: a NAD+ dependent deacetylase

Currently, Senior Group Leader, Aurigene Discovery Technologies, Bengaluru

Synergy between enhanced transcriptional strength of the viral promoter and the Tat - autoregulatory circuit accelerates latency establishment in HIV-1C 

Regulation of Acetylation- Dependent Chromatin transcription by Human Nucleophosmin, a Histone Chaperone

Insights into the Regulatory Mechanisms of Xenophagy as Revealed by Chemical Genetics

Metabolic significance of fumarate in plasmodium falciparum and biochemical and structural characterization of class I fumarate hydratase from plasmodium falciparum and methanocaldococcus jannaschii

Currently, Post-doctoral fellow, Weizmann Institute of Science, Israel

'Mrhl' long Non-coding RNA: Role in the Regulation of Wnt Signaling and Gene Expression.

Currently, Research Associate at Chromatin Biology Lab, MBGU, JNCASR.