2D semiconductors

Our expertise is in the synthesis of 2D nanosheet materials through liquid exfoliation and chemical exfoliation, and their chemical functionalization. We focus on the chemistries of phosphorene, arsenene, and transition metal dichalcogenides (TMDs) and are interested in their optical and electronic properties.

Neurodegeneration and Autophagy

 

The selective branch of autophagy that deals with identification, capture and degradation of protein aggregates is called aggrephagy. In neurodegenration, essential protein quality control mechanisms fail as the constituent components also find themselves trapped in the aggregates. Thus, although cellular aggrephagy has the potential to be upregulated, its dysfunction further aggravates the pathogenesis.

 

Unconventional Protein Secretion

 

Unconventional protein secretion (UCPS) of leaderless proteins bypasses the conventional endoplasmic reticulum (ER)-Golgi route. The proportion of UCPS in the secretome varies tremendously across eukaryotes. Interestingly, macroautophagy, an intracellular recycling process that is generally involved in cargo degradation, also participates in UCPS.

 

 

Water Purification

Water contamination by toxic heavy metals such as Pb2+, Hg2+ and Cd2+ and radioactive fission product of nuclear waste is becoming an increasingly important issue in separation science and environmental remediation. Our group designs low cost, wide pH range stable, layered chalcogenides based adsorbents for efficient removal of dissolved contaminants from ppb level with high sorption capacity. We are also interested in designing filtration-unit prototypes for water purification.

Halide Based Perovskites

Our group is interested in the fundamental research on halide based perovskites. Mostly, we synthesize these materials via mechanochemistry and simple solution based route. We extensively study the chemical and structural transformations of these perovskites. Along with that we are also interested to explore the photophysical properties of these materials.

Antimicrobial hydrogels/sealants

Hydrogels are promising candidates for delivering antibacterial agents to site of infection owing to their multitude of advantages such as controlled release, biocompatible nature, water retention capacity. We have explored our biomaterials research spectrum by developing polymeric hydrogels which have shown the potential of treating skin tissue infections in-vivo. Such approach can be useful to prevent surgical site infections, one of the major hospital-acquired infections claiming a high number of lives worldwide.

Antimicrobial surface coatings

In the current times of the dangerously spreading and infectious COVID-19, the need for preventive strategies is being reiterated extensively.  We have contributed on that front through the development of antibacterial and antifungal coatings which can prevent the spread of infections. Our development includes antimicrobial paints based on polymers and polymeric nanocomposites. We have also developed antimicrobial paints from biodegradable antibacterial polymers. These paints have shown marked reduction in medical device (i.e.