Infectious diseases remain a major threat to global health and are now the
world’s biggest killers, causing over 15 million deaths per year. The threat
is compounded by the fact that an increasing percentage of pathogens are
developing resistance against the available arsenal of drugs. Therefore there
is an urgent need for a well-coordinated and integrated approach to tackle the
threat of infectious diseases. Our laboratory seeks to provide a platform to
integrate organic chemistry and material science with biology to combat
infectious diseases in a multipronged approach, namely, diagnosis, prevention
and treatment. Our research focuses on fundamental understanding of
material-pathogen interaction and development of innovative strategies that
will provide solutions in tackling infections. We are involved in creating
novel antimicrobial agents for the prevention and treatment of infectious
diseases and combating the emergence of antimicrobial resistance.
Additionally, we are interested in developing nanotechnology based smart drug
delivery systems for addressing nonspecific action and toxicity related issues
of existing drugs for indications like infectious diseases. We are also
interested in engineering hydrogel based bioadhesive and wound-healing
materials.
Since we are involved in rational design of therapeutics, we support our
chemical designs with theoretically generated models to get better insights
into drug-target relationships.
Our team consists of researchers from various disciplines like organic
chemistry, material science and biology. Our laboratory is well equipped to
conduct research on bio-organic and medicinal chemistry at the highest level.
We welcome to our group motivated researchers with a passion for science.
Please take a look at the specific details of our research and feel free to
write to us with your queries.
With best regards,
Jayanta Haldar
Specific Areas of Research
https://www.jncasr.ac.in/faculty/jayanta/research-area/semi-synthetic-glycopeptide
