Students

Shobith Suresh pursuing Ph.D.

Educational Background :

Msc in Virology from Amity Institute Of Virology & Immunology, Amity University, Uttar Pradesh. 

BSc in Microbiology from Kannur University, Kerala.

Email : shobith[at]jncasr[dot]ac[dot]in

Research :

My work is to decipher the role of Tat-PTM and the RBEIII motif on HIV-1 latency. To evaluate the influence of Tat-PTM on HIV-1 latency, I will generate subsets of cells representing different stages of latency and simultaneously raise Tat-PTM-specific polyclonal antibodies in rabbits. Diverse experimental strategies, including flow cytometry, mass spectrometry, CUT&Tag, Immunoprecipitation, Proximity ligation assay etc., will be used to understand how Tat-PTM might influence HIV-1 latency. I also aim to decipher the influence of the RBEIII motif and its duplication on HIV-1 transcription. To achieve this, I will characterize the functioning of the RBEIII motif of HIV-1C and the nature of the TF profile recruited under various experimental conditions.

Chhavi Saini pursuing Integrated Ph.D

Function of Tat is very well established for active viral transcription, by recruiting components of host transcriptional machinery. Recent findings from our laboratory demonstrating a positive correlation between the transcriptional strength of the viral promoter and the rate of latency establishment in HIV-1 allude to a direct role for Tat in latency establishment. In other words, Tat may demonstrate context-dependent and diametrically opposite effects on viral transcription, activating, or suppressing viral gene expression. My work is to find post-translational modifications of Tat at different phases of viral gene expression which could determine the positive or negative influence on viral transcription.

Email - chhavi[at]jncasr[dot]ac[dot]in

Hrimkar pursuing Ph.D.

Academic Background:

Bsc. in Biochemistry from St. Xavier's College, Ahmedabad, Gujarat

MSc. in Biochemistry from Institute of Science, Nirma University, Ahmedabad, Gujarat

Email - hrimkarbuch[at]jncasr[dot]ac[dot]in

Swarnima Mishra pursuing Ph.D.

I work on understanding the correlation of HIV promoter (LTR) variants with viral reservoir characteristics and its modulation in context of disease progression.

Email - swarnima[at]jncasr[dot]ac[dot]in

Riya Manna pursuing Ph.D.

Educational Background-

MSc in Biomedical Science from Dr B. R. Ambedkar Center for Biomedical Research, University of Delhi.

BSc in Life Science from Gargi College, University of Delhi.

Email : riyamanna[at]jncasr[dot]ac[dot]in

Manisha Sharma pursuing Ph.D.

Academic Background

Bachelor's - Govt. G.D. Girls College, (RRBMU), Alwar, Rajasthan 

Masters - School of Life Sciences, Jawaharlal Nehru University, New Delhi

Email - manisha[at]jncasr[dot]ac[dot]in

Abhilash Jeas George pursuing Ph.D.

Bachelors: B.Sc. (Hons.) Microbiology, Ram Lal Anand College, University of Delhi

Masters: M.Sc. Microbiology, Department of Biotechnology, Cochin University of Science and Technology

abhilash[at]jncasr[dot]ac[dot]in

Venkateswaran M pursuing Integrated Ph.D

Academic background

Bachelors: BSc, Life Sciences, Central University of Tamil Nadu, Thiruvarur.

venkateswaran@jncasr.ac.in