PhD student Mansi Rathi wins a poster award for her poster on the analyses of sleep patterns in Early and Late Chronotypes of Drosophila melanogaster

"Under warm ambient conditions, Drosophila melanogaster suppresses nighttime activity via the neuropeptide PDF" Aishwariya Srikala Iyengar, Rutvij Kaustubh Kulkarni & Vasu Sheeba in Genes Brain Behavior

"VANESSA – Shiny apps for accelerated time-series analysis and visualization of Drosophila circadian rhythm and sleep data" Arijit Ghosh & Vasu Sheeba in Journal of Biological Rhythms 

Why motion makes you sleepy: Insight from fruit flies

by Society for Neuroscience

Why motion makes you sleepy: Insight from fruit flies
Experimental setup and design. Credit: Lone et al., JNeurosci 2021

People fall asleep on long car rides, fussy babies can be lulled to sleep in a rocking chair, and fruit flies in a tube doze off while spinning in slow circles. The mechanism behind motion-induced sleep is unclear in humans, but in fruit flies, it depends on motion-sensitive neurons in sensory organs, according to new research published in The Journal of Neuroscience.

Lone et al. monitored the sleep of  while they were moved in circles on a shaker. They repeated the experiment during the day and the night and on several genetic strains of flies. Slow rotational speeds increased the frequency of daytime sleep in both male and female flies. The effect continued in flies missing key circadian clock genes, indicating the mechanism does not rely on the time of day.

The research team also investigated the role of nanchung receptors, an ion channel abundant in sensory organs that is sensitive to vibrations, , and other mechanical sensations. Motion-induced sleep did not occur as often in the genetic strain of fly lacking nanchung-expressing neurons. Physically removing the nanchung neurons reduced the effect even more. There may be a similar mechanism behind motion-induced sleep in humans via vibration-sensitive cells in the ear.

Eligilbility - MSc in Biological Sciences with at least 2-3 years experience in Drosophila handling and immunohistochemical procedures. 

Apply by email to sheeba@jncasr.ac.in within March 23rd 2021.