Prof. Maneesha Inamdar is a cell and developmental biologist with several years of experience in a comparative analysis of cardiovascular development. She initiated both teaching and contemporary research in the area of stem cells and developmental biology at the JNCASR. Prof. Inamdar’s group has established human embryonic stem cell lines in India and worked extensively on mammalian cardiovascular development. Her laboratory studies cell lineage specification and differentiation during development. They have taken a unique comparative approach using embryonic stem cell models, mouse developmental biology and transgenics, and Drosophila genetics, to decipher the roles of novel genes expressed early in the blood and cardiovascular system. Their current focus is on analyzing mammalian development using stem cell models as well as clinical studies.
The Inamdar laboratory derived the first well-characterized human embryonic stem cell lines representing the Indian ethnic background- importantly, these were from unusable, discarded embryos. They established novel protocols to generate cardiomyocytes from these cells. The cell lines are deposited in the UK Stem Cell Bank and have been distributed worldwide and included in the International Stem Cell Initiative (ISCI2) project involving 22 countries - which is the only contribution from India in this project. Indian researchers now have internationally accepted indigenous stem cells which provide a unique platform for genetic and chemical screens and developing therapies. They have also generated and characterized mouse and human induced pluripotent stem (iPS) cells with the aim to use patient-derived iPS cells as disease models.
Prof. Inamdar has actively participated in collaborative research with several leaders in the field of stem cell and cardiovascular biology through international programs funded by the UK India Education and Research Initiative (UKIERI), Indo US Science and Technology Forum (IUSSTF) and The Wellcome Trust, UK. She participated in and organized several national and international meetings in the area of stem cells. She has trained over eighty researchers in stem cell culture and is currently the member of WHO expert advisory committee on Developing global standards for governance and oversight of Human Genome editing.
2019 - present Chair, Molecular Biology and Genetics Unit, JNCASR
2019 - present Visiting Professor, Tata Institute for Genetics and Society (TIGS)
2015 - 2019 Dean, Fellowships and Extension Programmes, JNCASR
2012 - present Professor, JNCASR
2009 - present Adjunct Professor, Institute for Stem Cell Biology and Regenerative Medicine, (inStem), Bangalore.
Awards and Fellowships
2019 J C Bose Fellowship
2018 Fellow, Indian National Science Academy
2017 Dr. Kalpana Chawla Award
2017 Fellow, Indian Academy of Sciences
2011 National Young Woman Bioscientist Award (Dept. of Biotechnology, Govt. of India)
2011 National Bioscience Award for Career Development (Dept. of Biotechnology, Govt. of India)
1999 - 2002 Young Associate of the Indian Academy of Sciences.
SERB, Department of Biotechnology (DBT)
Department of Science and Technology (DST)
Council of Scientific and Industrial Research (CSIR)
The UK India Education and Research Initiative (UKIERI)
Indo-US Science and Technology Forum (IUSSTF)
Indo-Danish programme under DBT
The Indo-French Centre for the Promotion of Advanced Research (CEFIPRA)
Expert advisory committee on Developing global standards for governance and oversight of Human Genome editing, WHO
Indian Society of Developmental Biologists
Indian Society of Cell Biology
Society for Developmental Biology, USA
International Society for Stem Cell Research (ISSCR), USA
International Society for Experimental Hematology
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